Alkaloids and anthraquinones from branches and leaves of uvaria kurzii.

Author: Ziming LV ^{1
,

2} ; Qingjian ZHANG ; Ruoyun CHEN ; Dequan YU
Author Information

1. Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. aabben@
2. com
Publication Type:Journal Article
MeSH: Alkaloids; chemistry; Anthraquinones; chemistry; Aporphines; chemistry; Emodin; analogs & derivatives; chemistry; Magnetic Resonance Spectroscopy; Plant Leaves; chemistry; Plant Stems; chemistry; Uvaria; chemistry
From: China Journal of Chinese Materia Medica 2011;36(9):1190-1192
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo investigate the chemical constituents of the branches and leaves of Uvaria kurzii.
METHODThe compounds were isolated and purified by silica gel and Sephadex LH-20 column chromatographic methods. Their chemical structures were elucidated on the basis of physicochemical properties and spectral data.
RESULTNine compounds were isolated and identified as: bidebiline A(1), annobraine (2), oxoputerine (3), atherospermidine (4), liriodenine (5), physcion (6), questin (7), rubiadin 3-methyl ether (8), emodin (9).
CONCLUSIONCompound 1-4, 6-9 were isolated from the genus Uvaria for the first time. Compound 3-5 showed inhabitation activities against tumor cell lines A549, Bel7402, BGC823, HCT-8, A2780, respectively.