Relationship between serum HBV DNA levels and serum hyaluronic acid levels in hepatitis B cirrhosis patients.
- Author:
Hong-Yi LI
1
;
Zhong DONG
;
Hong MA
Author Information
- Publication Type:Journal Article
- MeSH: Adult; DNA, Viral; blood; genetics; Female; Hepatitis B virus; genetics; Hepatitis B, Chronic; complications; Humans; Hyaluronic Acid; blood; Liver Cirrhosis; blood; etiology; Male; Middle Aged; Polymerase Chain Reaction; methods; Radioimmunoassay; methods
- From: Chinese Journal of Experimental and Clinical Virology 2007;21(3):256-257
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo probe the relationship between serum HBV DNA levels and serum hyaluronic acid (HA) levels in hepatitis B cirrhosis patients.
METHODSOf 62 patients diagnosed with hepatitis B cirrhosis serum HBV DNA was determined by fluorescent quantitative PCR. Serum HA was determined by radioimmunity assay. The relationship between serum HBV DNA levels and serum HA levels was probed.
RESULTSSerum HA of hepatitis B cirrhosis patients increased significantly and increased with the Child grade ascending (P less than 0.05). But serum HA levels had no significant correlation with serum HBV DNA levels (P greater than 0.05).
CONCLUSIONSerum HBV DNA levels had no significant correlation with liver cirrhosis grades and serum HA levels in hepatitis B cirrhosis patients.
