Clinical characteristics of 104 patients with primary gastrointestinal non-Hodgkin lymphoma.

Yuehua HUANG; Daobin ZHOU; Minghui DUAN; Jian LI; Bing HAN; Junling ZHUANG; Wei ZHANG

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Clinical characteristics of 104 patients with primary gastrointestinal non-Hodgkin lymphoma.

VernacularTitle:104例原发胃肠道非霍奇金淋巴瘤患者临床特征及预后分析
Author: Yuehua HUANG ¹ ; Daobin ZHOU ¹ ; Minghui DUAN ¹ ; Jian LI ¹ ; Bing HAN ¹ ; Junling ZHUANG ¹ ; Wei ZHANG ¹
Author Information

1. Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Publication Type:Journal Article
MeSH: Adolescent; Adult; Aged; Aged, 80 and over; Disease-Free Survival; Female; Gastrointestinal Neoplasms; diagnosis; Humans; Lymphoma, Non-Hodgkin; diagnosis; Male; Middle Aged; Prognosis; Retrospective Studies; Young Adult
From: Chinese Journal of Hematology 2014;35(9):791-795
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo analyze the clinical characteristics and prognostic factors in patients with primary gastrointestinal non-Hodgkin lymphoma (PGI-NHL).
METHODSThe pathological data of 104 PGI-NHL patients diagnosed in our hospital between 2003 and 2013 were analyzed retrospectively.
RESULTS104 patients with PGI-NHL were enrolled, including 58 males and 46 females with a median age of 53 (range:15 to 83) years. 51(49%) cases derived from stomach and the other 53 (51%) patients originated in intestine. The median survival was 35 (range:1 to 30) months. The 1- year, 3- year, and 5-year overall survival (OS) were 88.4%, 80.7% and 78.8%, respectively. Both progress free survival and OS were significantly higher in B-cell GPI-NHL than T- cell GPI-NHL (P=0.000).
CONCLUSIONThe survival of gastric NHL is superior to intestinal NHL. The sites of origin and pathological type are prognostic factors for survival in PGI-NHL patients.