A Case of Primary Pulmonary Sarcoma with Morphologic Features of Malignant Fibrous Histiocytoma.
10.4046/trd.2002.52.2.186
- Author:
Youn Jeong LEE
1
;
Won Haing HUR
;
Dae Keun LO
;
Seung Joon KIM
;
Sook Young LEE
;
Young Kyoon KIM
;
Hwa Sik MOON
;
Jeong Sup SONG
;
Sung Hak PARK
;
Gyeong Sin PARK
;
Kyo Young LEE
Author Information
1. Department of Internal Medicine, Catholic University of Korea, School of Medicine, Seoul, Korea. cmcpsh@cmc.cuk.ac.kr
- Publication Type:Case Report
- Keywords:
Malignant fibrous histiocytoma;
Lung sarcoma;
Vimentin
- MeSH:
Adult;
Biopsy;
Desmin;
Histiocytoma, Malignant Fibrous*;
Humans;
Keratins;
Lung;
Lung Neoplasms;
Middle Aged;
Neoplasm Metastasis;
Pleural Effusion;
Radiography, Thoracic;
Ribs;
Sarcoma*;
Soft Tissue Neoplasms;
Tomography, X-Ray Computed;
Vimentin
- From:Tuberculosis and Respiratory Diseases
2002;52(2):186-191
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A malignant fibrous histiocytoma is a malignant soft tissue neoplasm that occurs frequently in the metaphyseal ends of the long bones of adults. The lung is a common site for metastasis but it is a rare site for a primary malignant fibrous histiocytoma. Here we report a case of a primary malignant fibrous histiocytoma of the lung. The patient was a 53-year-old man who presented with a moderate amount of a left pleural effusion and an ill-defined mass in the left lower lobe on a chest radiograph and a local invasion to the left 10th and 11th rib on chest CT. Under the strong suspicion of lung cancer with a pleural invasion, a serial diagnostic thoracentesis was performed. The cytologic examination of the pleural effusion revealed no malignant cells. Consequently, a thoracoscopic pleural biopsy was performed. The histological examination revealed slender spindle cells and scattered epitheloid cells arranged in a vague storiform or a whirling pattern. Immunohistochemically, the tumor cells tested positive for vimentin and negative for cytokeratin, desmin, CD34 and PAS. These features were consistent with a malignant fibrous histiocytoma. This case is an unusual addition to the small number of published reports on a primary malignant fibrous histiocytoma of the lung.
