Acquired Long QT Syndrome Manifesting with Torsades de Pointes in a Patient with Panhypopituitarism due to Radiotherapy.
10.4070/kcj.2013.43.5.340
- Author:
Dae Gil KANG
1
;
Sung Eun KIM
;
Myoung Soo PARK
;
Eun Jung KIM
;
Jun Hee LEE
;
Dae Gyun PARK
;
Kyoo Rok HAN
;
Dong Jin OH
Author Information
1. Division of Cardiology, Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University Medical Center, Seoul, Korea. drhyangii@hallym.or.kr
- Publication Type:Case Report
- Keywords:
Tachycardia, ventricular;
Torsades de pointes;
Hypopituitarism;
Radiotherapy
- MeSH:
Arrhythmias, Cardiac;
Humans;
Hypopituitarism;
Long QT Syndrome;
Magnesium;
Male;
Sepsis;
Tachycardia, Ventricular;
Thyroid Gland;
Thyroid Hormones;
Torsades de Pointes;
Urinary Tract Infections
- From:Korean Circulation Journal
2013;43(5):340-342
- CountryRepublic of Korea
- Language:English
-
Abstract:
We describe a 64-year-old male patient with panhypopituitarism who experienced polymorphic ventricular tachycardia (VT) associated with long QT intervals. The panhypopituitarism developed as a sequelae of radiation therapy administered 20 years prior to his current presentation and was recently aggravated by urinary tract infection with sepsis. In this case, polymorphic VT was resistant to conventional therapy (including magnesium infusion), and QT prolongation and T wave inversion were normalized after the administration of steroid and thyroid hormones. Thyroid hormone is generally known to be associated with torsades de pointes (TdP), but steroid or other hormones may also provoke TdP. Hormonal disorders should be considered as a cause of polymorphic VT with long QT intervals. Some arrhythmias can be life-threatening, and they can be prevented with supplementation of the insufficient hormone.
