Laparoscopic cholecystectomy under spinal-epidural anesthesia vs. general anaesthesia: a prospective randomised study.
	    		
		   		
		   			
		   		
	    	
    	 
    	10.4174/astr.2017.92.3.136
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Turgut DONMEZ
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Vuslat Muslu ERDEM
			        		
			        		;
		        		
		        		
		        		
			        		Sinan UZMAN
			        		
			        		;
		        		
		        		
		        		
			        		Dogan YILDIRIM
			        		
			        		;
		        		
		        		
		        		
			        		Huseyin AVAROGLU
			        		
			        		;
		        		
		        		
		        		
			        		Sina FERAHMAN
			        		
			        		;
		        		
		        		
		        		
			        		Oguzhan SUNAMAK
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Department of General Surgery, Lutfiye Nuri Burat State Hospital, Istanbul, Turkey. surgeont73@hotmail.com
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Original Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Laparoscopic cholecystectomy;
			        		
			        		
			        		
				        		General anesthesia;
			        		
			        		
			        		
				        		Epidural anesthesia;
			        		
			        		
			        		
				        		Spinal anesthesia
			        		
			        		
	        			
        			
        		
 
        	
            
            	- MeSH:
            	
	        			
	        				
	        				
				        		
					        		Anesthesia*;
				        		
			        		
				        		
					        		Anesthesia, Epidural;
				        		
			        		
				        		
					        		Anesthesia, General;
				        		
			        		
				        		
					        		Anesthesia, Spinal;
				        		
			        		
				        		
					        		Cholecystectomy, Laparoscopic*;
				        		
			        		
				        		
					        		Fentanyl;
				        		
			        		
				        		
					        		Headache;
				        		
			        		
				        		
					        		Humans;
				        		
			        		
				        		
					        		Hypotension;
				        		
			        		
				        		
					        		Incidence;
				        		
			        		
				        		
					        		Pain, Postoperative;
				        		
			        		
				        		
					        		Pneumoperitoneum;
				        		
			        		
				        		
					        		Postoperative Nausea and Vomiting;
				        		
			        		
				        		
					        		Prospective Studies*;
				        		
			        		
				        		
					        		Shoulder Pain;
				        		
			        		
				        		
					        		Urinary Retention
				        		
			        		
	        			
	        			
            	
            	
 
            
            
            	- From:Annals of Surgical Treatment and Research
	            		
	            		 2017;92(3):136-142
	            	
            	
 
            
            
            	- CountryRepublic of Korea
 
            
            
            	- Language:English
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	PURPOSE: Laparoscopic cholecystectomy (LC) is usually performed under the general anesthesia (GA). Aim of the study is to investigate the availability, safety and side effects of combined spinal/epidural anesthesia (CSEA) and comparison it with GA for LC. METHODS: Forty-nine patients who have a LC plan were included into the study. The patients were randomly divided into GA (n = 25) and CSEA (n = 24) groups. Intraoperative and postoperative adverse events, postoperative pain levels were compared between groups. RESULTS: Anesthesia procedures and surgeries for all patients were successfully completed. After the organization of pneumoperitoneum in CSEA group, 3 patients suffered from shoulder pain (12.5%) and 4 patients suffered from abdominal discomfort (16.6%). All these complaints were recovered with IV fentanyl administration. Only 1 patient developed hypotension which is recovered with fluid replacement and no need to use vasopressor treatment. Postoperative shoulder pain was significantly less observed in CSEA group (25% vs. 60%). Incidence of postoperative nausea and vomiting (PONV) was less observed in CSEA group but not statistically significant (4.2% vs. 20%). In the group of CSEA, 3 patients suffered from urinary retention (12.5%) and 2 patients suffered from spinal headache (8.3%). All postoperative pain parameters except 6th hour, were less observed in CSEA group, less VAS scores and less need to analgesic treatment in CSEA group comparing with GA group. CONCLUSION: CSEA can be used safely for laparoscopic cholecystectomies. Less postoperative surgical field pain, shoulder pain and PONV are the advantages of CSEA compared to GA.