Tc-99m MAG3 Renal Scan in Children: A Comparative Study with I-131 Hippuran Renal Scan.
- Author:
Dae Young KIM
1
;
Chun Il KIM
;
Seok Kil ZEON
;
Jung Ae HYUN
;
Kwang Sae KIM
Author Information
1. Department of Urology, and Institute for Medical Science, Keimyung University, School of Medicine, Taegu, Korea.
- Publication Type:Comparative Study ; Original Article
- Keywords:
Renal scan;
Tc-99m MAG3;
I-131 OIH;
Children
- MeSH:
Child*;
Humans;
Kidney;
Urinary Tract
- From:Korean Journal of Urology
1995;36(8):835-842
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
To investigate the efficacy of Tc-99m MAG3 for renal scan, the images and renograms of Tc-99m MAG3 were compared to those of I-131 hippuran. Tc-99m MAG3 diuretic renal scan and I-131 hippuran diuretic renal scan were undertaken in 16 children with upper urinary tract anomalies within the time interval of 2 to 3 days. Their ages ranged from 1 week to 11 years old, and the male-to-female ratio was 14 to 2. Of these patients, 9 patients were less than 1 year old. The spectrum of upper urinary tract anomalies were unilateral ureteropelvic junction obstruction in 7 cases, bilateral ureteropelvic junction obstruction in 5 cases, bilateral non-obstructing non-refluxing megaureter, unilateral non-obstructing non-refluxing megaureter, bilateral obstructing megaureter and unilateral ulticystic dysplastic kidney in 1 case respectively. The images of Tc-99m MAG3 showed better resolution than those of I- 131 hippuran. The parameters of the Tc-99m MAG3 renogram in total functioning renal units, such as time to peak renal activity(r=0.98), half-time clearance to peak(r=0.88), half-time clearance after diuretic injection(r=0.96) and relative renal function(r=0.90), were correlated well with those of I-131 hippuran. In conclusion, Tc-99m MAG3 diuretic renal scan is considered to have a high potential to replace I-131 hippuran in routine radionuclide renal studies as well as renal tubular function test.
