Feasibility of three-dimensional reconstruction and automated measurement of fetal long bones using 5D Long Bone.
10.5468/ogs.2015.58.4.268
- Author:
Hyewon HUR
1
;
Young Han KIM
;
Hee Young CHO
;
Yong Won PARK
;
Hye Sung WON
;
Mi Young LEE
;
Bo Hyon YUN
;
Kwang Hee LEE
;
Sung Yoon KIM
;
Junsang YOO
;
Ja Young KWON
Author Information
1. Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Yonsei University Health System, Yonsei University College of Medicine, Seoul, Korea. jaykwon@yuhs.ac
- Publication Type:Original Article
- Keywords:
5D Long Bone;
Fetal biometry;
Fetal long bone;
Three-dimensional ultrasound;
Two-dimensional ultrasound
- MeSH:
Female;
Femur;
Fetus;
Fibula;
Humans;
Mothers;
Observer Variation;
Pregnancy;
Pregnancy, Multiple;
Prospective Studies;
Tibia;
Ultrasonography
- From:Obstetrics & Gynecology Science
2015;58(4):268-276
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: To evaluate the feasibility of five-dimensional Long Bone (5D LB), a new technique that automatically archives, reconstructs images, and measures lengths of fetal long bones, to assess whether the direction of volume sweep influences fetal long bone measurements in three-dimensional (3D) ultrasound and 5D LB, and to compare measurements of fetal long bone lengths obtained with 5D LB and those obtained with conventional two-dimensional (2D) and manual 3D techniques. METHODS: This prospective study included 39 singleton pregnancies at 26+0 to 32+0 weeks of gestation. Multiple pregnancies, fetuses with multiple congenital anomalies, and mothers with underlying medical diseases were excluded. Fetal long bones of the lower extremities-the femur, tibia, and fibula were measured by 2D and 3D ultrasound, and 5D LB, by an expert and non-expert examiner. First, we analyzed the 3D ultrasound and 5D LB data according to 2 different sweeping angles. We analyzed intra- and inter-observer variability and agreement between ultrasound techniques. Paired t-test, interclass correlation coefficient, and Bland-Altman plot and Passing-Bablok regression were used for statistical analysis. RESULTS: There was no statistical difference between long bone measurements analyzed according to 2 different volume-sweeping angles by 3D ultrasound and 5D LB. Intra- and inter-observer variability were not significantly different among all 3 ultrasound techniques. Comparing 2D ultrasound and 5D LB, the interclass correlation coefficient for femur, tibia, and fibula was 0.91, 0.92, and 0.89, respectively. CONCLUSION: 5D LB is reproducible and comparable with conventional 2D and 3D ultrasound techniques for fetal long bone measurement.
