Clinical Features of Right-Sided Infective Endocarditis Occurring in Non-Drug Users.
10.3346/jkms.2014.29.6.776
- Author:
Mi Rae LEE
1
;
Sung A CHANG
;
Soo Hee CHOI
;
Ga Yeon LEE
;
Eun Kyoung KIM
;
Kyong Ran PECK
;
Seung Woo PARK
Author Information
1. Division of Cardiology, Department of Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea.
- Publication Type:Original Article
- Keywords:
Endocarditis;
Tricuspid Valve;
Echocardiography
- MeSH:
Adult;
Aged;
Central Venous Catheters/microbiology;
Echocardiography;
Endocarditis, Bacterial/*diagnosis/microbiology/mortality;
Female;
Heart Defects, Congenital/complications/epidemiology;
Hospital Mortality;
Humans;
Incidence;
Male;
Middle Aged;
Prognosis;
Retrospective Studies;
Staphylococcus aureus/isolation & purification;
Viridans Streptococci/isolation & purification;
Young Adult
- From:Journal of Korean Medical Science
2014;29(6):776-781
- CountryRepublic of Korea
- Language:English
-
Abstract:
Right-sided infective endocarditis (RIE) occurs predominantly in intravenous drug users in western countries, and it has a relatively good prognosis. Clinical features and prognosis of RIE occurring in non-drug users are not well known. We investigated the clinical findings of RIE in non-drug users. We retrospectively reviewed 345 cases diagnosed with IE. Cases with RIE or left-sided infective endocarditis (LIE) defined by the vegetation site were included and cases having no vegetation or both-side vegetation were excluded. Clinical findings and in-hospital outcome of RIE were compared to those of LIE. Among the 245 cases, 39 (16%) cases had RIE and 206 (84%) cases had LIE. RIE patients were younger (40+/-19 yr vs 50+/-18 yr, P=0.004), and had a higher incidence of congenital heart disease (CHD) (36% vs 13%, P<0.001) and central venous catheter (CVC) (21% vs 4%, P=0.001) compared to LIE patients. A large vegetation was more common in RIE (33% vs 9%, P<0.001). Staphylococcus aureus was the most common cause of RIE, while Streptococcus viridans were the most common cause of LIE. In-hospital mortality and cardiac surgery were not different between the two groups. CHD and use of CVC were common in non-drug users with RIE. The short-term clinical outcome of RIE is not different from that of LIE.
