Recurrent Mesalazine-Induced Myopericarditis in a Patient with Ulcerative Colitis.
10.4250/jcu.2012.20.3.154
- Author:
Eun Hye PARK
1
;
Byung Jin KIM
;
Jung Kwon HUH
;
Eun Haeng JEONG
;
Sang Hyuk LEE
;
Ki Bae BANG
;
Ji Soo SEOL
;
Joo Wook SUNG
;
Bum Soo KIM
;
Jin Ho KANG
Author Information
1. Division of Cardiology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea. bjjake.kim@samsung.com
- Publication Type:Case Report
- Keywords:
Myopericarditis;
Mesalazine;
Inflammatory bowel disease
- MeSH:
Adult;
Aspirin;
Colitis, Ulcerative;
Electrocardiography;
Fever;
Humans;
Inflammatory Bowel Diseases;
Male;
Mesalamine;
Pericarditis;
Rare Diseases;
Sulfasalazine;
Thorax;
Ulcer
- From:Journal of Cardiovascular Ultrasound
2012;20(3):154-156
- CountryRepublic of Korea
- Language:English
-
Abstract:
Inflammatory bowel disease (IBD) is considered as a dysregulated immune mediated disease. Pericarditis in IBD is a very rare disease both as an extra-intestinal manifestation of IBD and an adverse reaction of therapeutic drug for IBD such as mesalazine or sulfasalazine. A 26-year-old IBD male patient who had been taking mesalazine regularly for about 1 month was referred to our hospital because of fever, chest discomfort, and abnormal electrocardiographic findings. The patients was diagnosed as acute myopericarditis, and recovered after cessation of mesalazine using steroid and aspirin. When mesalazine was re-medicated some days after discharge, he suffered from myopericarditis again. Subsequently, myopericarditis was resolved just after cessation of mesalazine again. These findings suggest that the development of myopericarditis is caused by mesalazine.
