A Case of Hypersensitivity to Mosquito Bite Associated with Epstein-Barr Viral Infection and Natural Killer Cell Lymphocytosis.
10.3346/jkms.2010.25.2.321
- Author:
Eui Jung ROH
1
;
Eun Hee CHUNG
;
Young Pyo CHANG
;
Na Hye MYOUNG
;
Young Koo JEE
;
Min SEO
;
Jin Han KANG
Author Information
1. Department of Pediatrics, College of Medicine, Dankook University, Cheonan, Korea. ehchung@dankook.ac.kr
- Publication Type:Case Reports
- Keywords:
Hypersensitivity;
Culicidae;
Epstein-Barr Virus Infections;
Killer Cells, Natural;
Lymphocytosis
- MeSH:
Animals;
Child, Preschool;
Culicidae/*immunology;
Epstein-Barr Virus Infections/complications/*diagnosis;
Herpesvirus 4, Human/genetics/isolation & purification;
Humans;
Hypersensitivity/complications/*diagnosis;
Insect Bites and Stings/complications/*immunology;
Killer Cells, Natural/immunology/*pathology;
Lymphocytosis/complications/*diagnosis;
Male;
Polymerase Chain Reaction
- From:Journal of Korean Medical Science
2010;25(2):321-323
- CountryRepublic of Korea
- Language:English
-
Abstract:
Hypersensitivity to mosquito bites (HMB) is a disorder characterized by a necrotic skin reaction and generalized symptoms subsequent to mosquito bites. It has been suggested that HMB is associated with chronic Epstein-Barr virus (EBV) infection and natural killer cell leukemia/lymphoma. We describe here a Korean child who had HMB associated with chronic EBV infection and natural killer cell lymphocytosis. A 5-yr-old boy was suffered from necrotic skin lesions on the right ear lobe. Type A EB virus was detected from hlood cells and bone marrow biospy recognized hemophagocyrosis.
