Clinical Features of Patients with Anaphylaxis at a Single Hospital.
10.7581/pard.2012.22.3.232
- Author:
Hyang Mi PARK
1
;
Jin Chul NOH
;
Jong Hyun PARK
;
Youn Kyoung WON
;
Se Hee HWANG
;
Jae Yoon KIM
;
You Young KIM
;
Eui Jung ROH
;
Eun Hee CHUNG
Author Information
1. Department of Pediatrics, National Medical Center, Seoul, Korea. ehchung@nmc.or.kr
- Publication Type:Comparative Study ; Original Article
- Keywords:
Anaphylaxis;
Children;
Adult
- MeSH:
Adult;
Anaphylaxis;
Angioedema;
Child;
Emergencies;
Humans;
Inpatients;
Korea;
Medical Records;
Outpatients;
Prevalence;
Sex Ratio;
Urticaria
- From:Pediatric Allergy and Respiratory Disease
2012;22(3):232-238
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The studies concerning the clinical features of patients with anaphylaxis, who meet the newly established diagnostic criteria, are reported in Korea, but comparative studies regarding the clinical features of children and adult patients with anaphylaxis are lacking. The purpose of this study is to compare the clinical features of the children and adults with anaphylaxis, who meet the new diagnostic criteria at a single hospital. METHODS: We reviewed the medical records of patients who were diagnosed with anaphylaxis, anaphylactic shock, urticaria, and angioedema, including inpatients, outpatients and emergency room visited patients, at the National Medical Center from July, 2005 to August, 2011. The clinical characteristics of children and adults, who met the new diagnostic criteria for anaphylaxis, were analyzed. RESULTS: We identified 91 patients with anaphylaxis. Sixteen were children and 75 were adults. The sex ratio (male:female) and the mean age were 1:1.7 and 9.6 years among children, respectively, and 1:2.3 and 42.3 years, respectively, among adults. The most common cause of anaphylaxis based on clinical history was foods in 15 children (93.7%) and 35 adults (46.7%). Twelve children (75%) and 36 adults (48%) were rediagnosed with anaphylaxis. Patients with cardiovascular symptoms and severe severity were 1 (6.3%) and 1 (6.3%), respectively, among children, and 28 (37.3%) and 23 (30.3%), respectively, among adults. CONCLUSION: We rediagnosed some cases of anaphylaxis, using the new diagnostic criteria and most of the cases were diagnosed initially as urticaria or angioedema. The adults had more severe and more cardiovascular symptoms than children. In the future, a nationwide, multiinstitutional research will be necessary for the prevalence and the clinical features of anaphylaxis by the new diagnostic criteria in Korea.
