A Case of Hypothyroidism and Type 2 Diabetes Associated with Type V Hyperlipoproteinemia and Eruptive Xanthomas.
10.3346/jkms.2005.20.3.502
- Author:
Jeong Rang PARK
1
;
Tae Sik JUNG
;
Jung Hwa JUNG
;
Gyeong Won LEE
;
Me Ae KIM
;
Ki Jong PARK
;
Deok Ryong KIM
;
Se Ho CHANG
;
Soon Il CHUNG
;
Jong Ryeal HAHM
Author Information
1. Department of Internal Medicine, College of Medicine, Gyeongsang National University, Jinju, Korea. jrhahm@gshp.gsnu.ac.kr
- Publication Type:Case Report ; Research Support, Non-U.S. Gov't
- Keywords:
Hyperlipoproteinemia Type V;
Xanthomatosis;
Hypothyroidism;
Diabetes Mellitus;
Erythrocyte Aggregation
- MeSH:
Antilipemic Agents/therapeutic use;
Diabetes Mellitus, Type 2/blood/*complications/drug therapy;
Erythrocyte Aggregation;
Female;
Humans;
Hyperlipidemia/blood;
Hyperlipoproteinemia Type V/blood/*complications/drug therapy;
Hypoglycemic Agents/therapeutic use;
Hypothyroidism/blood/*complications/drug therapy;
Middle Aged;
Procetofen/therapeutic use;
Research Support, Non-U.S. Gov't;
Skin Diseases/blood/complications/drug therapy;
Thyrotropin/blood/therapeutic use;
Thyroxine/blood;
Treatment Outcome;
Xanthomatosis/blood/*complications/drug therapy
- From:Journal of Korean Medical Science
2005;20(3):502-505
- CountryRepublic of Korea
- Language:English
-
Abstract:
Primary hypothyroidism and type 2 diabetes are both typically associated with the increased level of triglycerides. To date, there have been only a few case reports of type 2 diabetes patients with both type V hyperlipoproteinemia and eruptive xanthomas, but there have been no reports of hypothyroidism patients associated with eruptive xanthomas. We report here on a case of a 48-yr old female patient who was diagnosed with type 2 diabetes and primary hypothyroidism associated with both type V hyperlipoproteinemia and eruptive xanthomas. We found rouleaux formation of RBCs in peripheral blood smear, elevated TSH, and low free T4 level, and dyslipidemia (total cholesterol 18.1 mM/L, triglyceride 61.64 mM/L, HDL 3.0 mM/L, and LDL 2.54 mM/L). She has taken fenofibrate, levothyroxine, and oral hypoglycemic agent for 4 months. After treatment, both TSH level and lipid concentration returned to normal range, and her yellowish skin nodules have also disappeared.
