Multifocal Osteosarcoma of the Skull: Multiple Primary or Metastatic? A Case Report.
	    		
		   		
	    	
    	
    	
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Hyuck CHO
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Bong Jin PARK
			        		
			        		;
		        		
		        		
		        		
			        		Yong Koo PARK
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Department of Pathology, Kyung Hee Medical Center, Kyung Hee University College of Medicine, Seoul, Korea. ykpark@khmc.or.kr
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Case Report
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Osteosarcoma;
			        		
			        		
			        		
				        		Skull;
			        		
			        		
			        		
				        		Multifocal
			        		
			        		
	        			
        			
        		
 
        	
            
            	- MeSH:
            	
	        			
	        				
	        				
				        		
					        		Drug Therapy;
				        		
			        		
				        		
					        		Female;
				        		
			        		
				        		
					        		Follow-Up Studies;
				        		
			        		
				        		
					        		Headache;
				        		
			        		
				        		
					        		Heart;
				        		
			        		
				        		
					        		Humans;
				        		
			        		
				        		
					        		Middle Aged;
				        		
			        		
				        		
					        		Osteoblasts;
				        		
			        		
				        		
					        		Osteosarcoma*;
				        		
			        		
				        		
					        		Pathology;
				        		
			        		
				        		
					        		Rabeprazole;
				        		
			        		
				        		
					        		Skull*
				        		
			        		
	        			
	        			
            	
            	
 
            
            
            	- From:Korean Journal of Pathology
	            		
	            		 2014;48(2):146-150
	            	
            	
 
            
            
            	- CountryRepublic of Korea
 
            
            
            	- Language:English
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Osteosarcoma of the skull is a very rare condition. Moreover, it is extremely rare for osteosarcoma to present as multiple lesions confined to the skull. A 58-year-old woman was admitted with two masses in the parietal area of the skull, accompanied by mild headache and tenderness. Imaging revealed two masses with a heterogeneous consistency in the cranial bones. Excision craniectomy was performed and the pathology was consistent with osteoblastic osteosarcoma. Two nodules in the heart were found on routine follow-up imaging while the patient was undergoing chemotherapy. The nodules were biopsied and found to be metastatic osteosarcoma.