Very Severe Aplastic Anemia appearing after Thymectomy.
- Author:
Chi Young PARK
1
;
Hee Je KIM
;
Yoo Jin KIM
;
Yoon Hee PARK
;
Jong Wook LEE
;
Woo Sung MIN
;
Chun Choo KIM
Author Information
1. Catholic Hemopoietic Stem Cell Transplantation Center, The Catholic University College of Medicine, Seoul, Korea. wsmin@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Aplastic anemia;
Thymoma;
Thymectomy;
Cyclosporine A
- MeSH:
Anemia, Aplastic/drug therapy/*etiology/*pathology;
Biopsy, Needle;
Bone Marrow/pathology;
Cyclosporine/administration & dosage;
Drug Therapy, Combination;
Female;
Follow-Up Studies;
Granulocyte Colony-Stimulating Factor/administration & dosage;
Humans;
Middle Aged;
Rare Diseases;
Risk Assessment;
Severity of Illness Index;
Thymectomy/*adverse effects/methods;
Thymoma/diagnosis/*surgery;
Treatment Outcome
- From:The Korean Journal of Internal Medicine
2003;18(1):61-63
- CountryRepublic of Korea
- Language:English
-
Abstract:
Aplastic anemia is a rare complication of thymoma and is extremely infrequent after thymectomy. We present a case of a 60-year-old woman with very severe aplastic anemia appearing sixteen months after thymectomy for a thymoma. She underwent thymectomy for a thymoma in April 2000. Preoperative examination revealed no hematologic abnormality. About sixteen months after the operation, she was readmitted because of pancytopenia with cough and fever. Bone marrow aspiration revealed a very severe hypoplasia in all the three cell lines with over 80% fatty tissue, and chest CT revealed no recurrence of thymoma. Her aplastic anemia had responded to cyclosporine A and granulocyte-colony stimulating factor (G-CSF).
