Peripheral eosinophilia - is it a predictable factor associated with eosinophilic cholecystitis?.
10.14701/kjhbps.2012.16.2.65
- Author:
Seung Seop YEOM
1
;
Ho Hyun KIM
;
Jung Chul KIM
;
Young Hoe HUR
;
Yang Seok KOH
;
Chol Kyoon CHO
;
Hyun Jong KIM
;
Sang Soo SHIN
;
Hyung Seok KIM
Author Information
1. Department of Surgery, Chonnam National University Medical School, Gwangju, Korea. 3rdvivace@hanmail.net
- Publication Type:Original Article
- Keywords:
Eosinophilic cholecystitis;
Eosinophilia;
Predictable factor;
Cholecystectomy
- MeSH:
Cholecystectomy;
Cholecystitis;
Eosinophilia;
Eosinophils;
Humans;
Multivariate Analysis;
Retrospective Studies
- From:Korean Journal of Hepato-Biliary-Pancreatic Surgery
2012;16(2):65-69
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUNDS/AIMS: The purpose of this study was to evaluate the role of peripheral eosinophilia as a predictable factor associated with Eosinophilic cholecystitis (EC) compared with other forms of cholecystitis in patients who underwent a cholecystectomy. METHODS: Between January 2001 and May 2011, the histopathologic features of 3,539 cholecystectomy specimens were reviewed retrospectively. EC was diagnosed in 30 specimens (0.84%). Data from 30 consecutive patients with EC (eosinophilic cholecystitis group [E-group]) were compared with a retrospective control group of 60 patients (other cholecystitis group [O-group]) during the same period. The two groups were matched for age, gender, and the presence of cholelithiasis. RESULTS: The median absolute eosinophil count 1 day post-operatively was 144 cells/mm3 (range: 9-801 cells/mm3) in the E-group and 93 cells/mm3 (range: 0-490 cells/mm3) in the O-group (p=0.036). Pre-operative peripheral eosinophilia was more common in the E-group than the O-group (20% vs. 3.3%, p=0.015). Multivariate analysis revealed that pre-operative peripheral eosinophilia was an independent significant predictable factor associated with EC (odds ratio=7.250, 1.365 <95% confidence interval<38.494, p=0.020). CONCLUSIONS: In the present study, pre-operative peripheral eosinophilia was shown to be an independent predictable factor associated with EC. Further researches seem to be necessary to confirm this finding.
