The Impact of the CHA₂DS₂-VASc Score on Recurrence of Atrial Fibrillation after a Single Catheter Ablation and Atrial Remodeling in Patients with Non-Valvular Atrial Fibrillation.
	    		
		   		
		   			
		   		
	    	
    	 
    	10.18501/arrhythmia.2017.002
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Chan Hee LEE
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Sang Hee LEE
			        		
			        		;
		        		
		        		
		        		
			        		Kyu Hwan PARK
			        		
			        		;
		        		
		        		
		        		
			        		Dong Gu SHIN
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Division of Cardiology, Department of Internal Medicine, Yeungnam University Hospital, Daegu, Republic of Korea. dgshin@med.yu.ac.kr
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Original Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Atrial Fibrillation;
			        		
			        		
			        		
				        		Catheter Ablation;
			        		
			        		
			        		
				        		Recurrence;
			        		
			        		
			        		
				        		Atrial Remodeling
			        		
			        		
	        			
        			
        		
 
        	
            
            	- MeSH:
            	
	        			
	        				
	        				
				        		
					        		Atrial Fibrillation*;
				        		
			        		
				        		
					        		Atrial Remodeling*;
				        		
			        		
				        		
					        		Catheter Ablation*;
				        		
			        		
				        		
					        		Catheters*;
				        		
			        		
				        		
					        		Humans;
				        		
			        		
				        		
					        		Recurrence*
				        		
			        		
	        			
	        			
            	
            	
 
            
            
            	- From:International Journal of Arrhythmia
	            		
	            		 2017;18(1):16-26
	            	
            	
 
            
            
            	- CountryRepublic of Korea
 
            
            
            	- Language:English
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	BACKGROUND AND OBJECTIVES: This study aimed to evaluate the impact of the CHA₂DS₂-VASc score on atrial fibrillation (AF) recurrence after a single catheter ablation procedure in patients with non-valvular AF. We also investigated the correlation between CHA₂DS₂-VASc score and atrial substrate. SUBJECTS AND METHODS: This study evaluated 151 patients who underwent catheter ablation of non-valvular AF. The study population was stratified into group 1 (<2, n=72) and group 2 (≥2, n=79) by CHA₂DS₂-VASc score. The CHA₂DS₂-VASc score was analyzed as a continuous and categorical value for evaluating its impact on AF recurrence after catheter ablation. The left atrial voltage data were analyzed by the categorical values of this score. RESULTS: Post-ablation recurrence (31.6% vs. 18.1%, p=0.046) was observed more frequently in group 2. The mean area of the lowvoltage zone was 75.64±24.81 cm² and 94.44±28.09 cm² in groups 1 and 2, respectively (p=0.005). The left atrial mean voltage in group 2 was 0.99±0.31 mV, significantly lower than that (1.49±0.67 mV, p=0.001) in group 1. The CHA₂DS₂-VASc score was the independent predictor with a modest predictive value for AF recurrence after catheter ablation. CONCLUSION: Our study showed that CHA₂DS₂-VASc score was associated with atrial remodeling and could be useful in stratifying post-ablation recurrence in patients with non-valvular AF.