The Study of Antithrombin III Deficiency in Patients with Recurrent Spontaneous Abortion.
- Author:
Yoon Sung NAM
;
Kwang Yul CHA
;
Nam Keun KIM
;
Myung Seo KANG
;
Doyeon OH
- Publication Type:Original Article
- Keywords:
Recurrent spontaneous abortion;
Antithrombin III deficiency
- MeSH:
Abortion, Habitual;
Abortion, Spontaneous*;
Antithrombin III Deficiency*;
Antithrombin III*;
Female;
Humans;
Incidence;
Lupus Coagulation Inhibitor;
Mass Screening;
Pregnancy
- From:Korean Journal of Fertility and Sterility
2001;28(4):301-306
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJETIVE: To analyze the antithrombin III deficiency in patients with recurrent spontaneous abortion. MATERIALS AND METHOD: The blood samples were tested by chromogenic assay to evaluate the activity of antithrombin III. RESULTS: There was only one case of antithrombin III deficiency. This patient experienced one neonatal death after delivery and one FDIU (fetal death in utero). And also this patient showed a lupus anticoagulant and the prolongation of PTT. CONCLUSIONS: Women with recurrent miscarriage who have no obvious identified cause should consider hematologic screening. Antithrombin III deficiency could be a cause of recurrent spontaneous abortion. But the incidence is very rare in Korean patients.
