A Cytogenetic Survey of the Mentally Retarded Children.
- Author:
Kap Soon JU
;
Hee Kyung LEE
- Publication Type:Original Article
- Keywords:
Karyotype;
Autosoome;
Sex Chromosome;
Mentally Retarded
- MeSH:
Abnormal Karyotype;
Child*;
Cytogenetics*;
Down Syndrome;
Female;
Humans;
Karyotype;
Male;
Mentally Disabled Persons*;
Seoul;
Sex Chromosomes
- From:Korean Journal of Obstetrics and Gynecology
2000;43(1):11-16
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: A cytogenetic survey of the mentally retarded children in Seoul City Welfare Center for the Mentally Retarded and St Peter school has been undertaken. METHODS: The chromosome analysis was carried out in 92 males and in 66 females as a total of 158 cases. RESULTS: Abnormal karyotypes were observed in 22.2% of the total cases (35/158). Autosome and sex chromosome anomaly were observed in 20.3%(32/158) and 1.9%(3/158) respectively. Of 35 cases of anomaly, 91.4%(32/35) was autosome anomaly and 8.6%(3/35), sex chromosome anomaly. CONCLUSION: Down syndrome karyotype was the most frequent anomaly among autosome anomalies which was 62.5%(20/32) and other autosome anomalies were observed in 37.5%(12/32).
