Anti-LGI1 Antibody Autoimmune Encephalitis Which Manifests Faciobrachial Dystonic Seizure.
- Author:
Hyunjin KIM
1
;
Bomi KIM
;
Jihye HWANG
;
Yoojin LEE
;
Soon Tae LEE
;
Joong Koo KANG
Author Information
1. Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. jkkang@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Autoimmune encephalitis;
LGI1;
Voltage gated potassium channel
- MeSH:
Aged;
Antibodies;
Anticonvulsants;
Arm;
Brain;
Encephalitis*;
Glioma;
Humans;
Immunotherapy;
Magnetic Resonance Imaging;
Potassium Channels, Voltage-Gated;
Seizures*
- From:Journal of the Korean Neurological Association
2014;32(1):22-25
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Anti-LGI1 (leucine-rich glioma inactivated-1) antibody encephalitis is one of autoimmune encephalitis. We report a 66-year-old man who presented with frequent, brief dystonic seizures which involve predominantly ipsilateral face and arm without cognitive impairment. Brain MRI showed normal finding. Serum and CSF tests revealed anti-LGI1 antibody. His symptom was not relieved by antiepileptic drugs, but completely controlled after immunotherapy. This case indicates that recognition of the brief, dystonic seizures should do tests for anti-LGI1 antibodies.
