Feasibility of Early and Repeated Low-dose Interscalene Brachial Plexus Block for Residual Pain in Acute Cervical Radiculopathy Treated with NSAIDS.
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3344/kjp.2014.27.2.125
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Toshio IWATA
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Mari MITORO
			        		
			        		;
		        		
		        		
		        		
			        		Naoya KUZUMOTO
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Department of Anesthesiology, Nara Prefectural Mimuro Hospital, Nara, Japan. notkorit4ky@yahoo.co.jp
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Original Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		acute;
			        		
			        		
			        		
				        		brachial plexus;
			        		
			        		
			        		
				        		cervical radiculopathy;
			        		
			        		
			        		
				        		low-dose;
			        		
			        		
			        		
				        		nerve block
			        		
			        		
	        			
        			
        		
 
        	
            
            	- MeSH:
            	
	        			
	        				
	        				
				        		
					        		Anti-Inflammatory Agents, Non-Steroidal*;
				        		
			        		
				        		
					        		Brachial Plexus*;
				        		
			        		
				        		
					        		Humans;
				        		
			        		
				        		
					        		Mepivacaine;
				        		
			        		
				        		
					        		Nerve Block;
				        		
			        		
				        		
					        		Outpatients;
				        		
			        		
				        		
					        		Pain Management;
				        		
			        		
				        		
					        		Patient Satisfaction;
				        		
			        		
				        		
					        		Prospective Studies;
				        		
			        		
				        		
					        		Radiculopathy*;
				        		
			        		
				        		
					        		Ultrasonography
				        		
			        		
	        			
	        			
            	
            	
 
            
            
            	- From:The Korean Journal of Pain
	            		
	            		 2014;27(2):125-132
	            	
            	
 
            
            
            	- CountryRepublic of Korea
 
            
            
            	- Language:English
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	BACKGROUND: To improve residual pain management in acute cervical radiculopathy treated with NSAIDs, the feasibility of early and repeated low-dose interscalene brachial plexus block (IS-BPB) needs to be assessed. METHODS: This was a prospective study on patients receiving NSAIDs (loxoprofen) for cervical radiculopathy of < or = 2-week onset. Pain was assessed using the visual analogue scale (VAS). A low-dose ultrasonography (USG)-guided IS-BPB (dexamethasone [1.65 mg; 0.5 ml] and mepivacaine [1%; 3.0 ml]) was performed at baseline and weekly thereafter for 4 weeks in an outpatient setting for the intervention group. All patients were evaluated using a visual satisfaction score (VSS) at week 4. Patients with baseline VAS scores < 70 (mild to moderate pain; MM group) and > or = 70 (severe pain; SE group) were compared to the controls receiving NSAIDs. RESULTS: A total of 316 IS-BPBs were performed in the intervention group. There was a significant difference in the decline in the VAS from week 0 to week 3 in the MM and SE groups (P < 0.05); however, from week 3 to week 4, the therapeutic effect exhibited no significant difference. Thirteen patients at week 2 (15.5%; MM: 27.7%; SE: 0%), 43 at week 3 (51.2%; MM: 83.0%; SE: 10.8%), and 47 at week 4 (56.0%; MM: 85.1%; SE: 18.9%) achieved a VAS score of < or = 20. Patient satisfaction was high, and the decrease in VAS scores in both groups was significant (P < 0.05) compared to the controls. CONCLUSIONS: Weekly, low-dose, USG-guided IS-BPB can be implemented for early pain relief in acute cervical radiculopathy, with high patient satisfaction.