Case of ABO-Incompatible Living Donor Kidney Transplantation without Blood Products in a Jehovah's Witness.
10.4285/jkstn.2011.25.1.38
- Author:
An Sook CHOI
1
;
Seong Min YU
;
Jin Ho LEE
;
Joon Suk OH
;
Seong Min KIM
;
Yong Hun SIN
;
Joong Kyung KIM
Author Information
1. Department of Internal Medicine, Bong Seng Memorial Hospital, Busan, Korea. syhpmj@hanmail.net
- Publication Type:Case Report
- Keywords:
ABO-incompatible kidney transplantation;
Clotting factors;
Jehovah's Witness
- MeSH:
Antibodies, Monoclonal, Murine-Derived;
Hemorrhage;
Humans;
Immunosuppressive Agents;
Kidney;
Kidney Transplantation;
Korea;
Living Donors;
Mycophenolic Acid;
Plasma;
Plasmapheresis;
Rituximab;
Splenectomy;
Tacrolimus;
Transplants;
Wit and Humor as Topic
- From:The Journal of the Korean Society for Transplantation
2011;25(1):38-42
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
ABO-incompatible kidney transplantations have been performed successfully in Korea without splenectomy using plasmapheresis, anti-CD20 monoclonal antibody infusions and other immunosuppressants. However, there is no report of a case of ABO-incompatible kidney transplantation in a Jehovah's Witness. Hence, we report our experience of successful ABO-incompatible kidney transplantation without blood products in a Jehovah's Witness. The recipient was treated with six sessions of plasmapheresis and he received intravenous rituximab before transplantation. Immunosuppressive regimen consisted of tacrolimus, mycophenolate mofetil and steroid. The replacement fluid for plasmapheresis was 5%% albumin solution instead of fresh frozen plasma. We measured the clotting factors before and after plasmapheresis and used cryoprecipitate to prevent bleeding.
