MRI Features of Hepatocellular Carcinoma Related to Biologic Behavior.
10.3348/kjr.2015.16.3.449
- Author:
Eun Suk CHO
1
;
Jin Young CHOI
Author Information
1. Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 135-720, Korea.
- Publication Type:Review
- Keywords:
Hepatocellular carcinoma;
Magnetic resonance imaging;
Prognosis
- MeSH:
Aged;
Biological Products;
Biomarkers, Tumor;
Carcinoma, Hepatocellular/diagnosis/pathology/*radiography;
Contrast Media;
Gadolinium DTPA;
Humans;
Liver Neoplasms/diagnosis/pathology/*radiography;
Magnetic Resonance Imaging/*methods;
Male;
Middle Aged;
Neoplasm Staging/methods;
Prognosis
- From:Korean Journal of Radiology
2015;16(3):449-464
- CountryRepublic of Korea
- Language:English
-
Abstract:
Imaging studies including magnetic resonance imaging (MRI) play a crucial role in the diagnosis and staging of hepatocellular carcinoma (HCC). Several recent studies reveal a large number of MRI features related to the prognosis of HCC. In this review, we discuss various MRI features of HCC and their implications for the diagnosis and prognosis as imaging biomarkers. As a whole, the favorable MRI findings of HCC are small size, encapsulation, intralesional fat, high apparent diffusion coefficient (ADC) value, and smooth margins or hyperintensity on the hepatobiliary phase of gadoxetic acid-enhanced MRI. Unfavorable findings include large size, multifocality, low ADC value, non-smooth margins or hypointensity on hepatobiliary phase images. MRI findings are potential imaging biomarkers in patients with HCC.
