Dietary Risk Factors in Relation to Colorectal Adenoma.
10.4166/kjg.2012.60.2.102
- Author:
Sun Young YANG
1
;
Young Sun KIM
;
Ji Hyun SONG
;
Su Jin CHUNG
;
In Hee LEE
;
Kyoung Ju HONG
;
Eun Jung LEE
;
Donghee KIM
;
Jeong Yoon YIM
;
Min Jung PARK
;
Seon Hee LIM
;
Joo Sung KIM
Author Information
1. Department of Internal Medicine, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, Korea. pandayoung@yahoo.co.kr
- Publication Type:Original Article ; English Abstract
- Keywords:
Colorectal neoplasms;
Adenoma;
Risk factors;
Diet;
Energy intake
- MeSH:
Adenoma/complications/*diagnosis;
Age Factors;
Alcohol Drinking;
Body Mass Index;
Case-Control Studies;
Colonoscopy;
Colorectal Neoplasms/complications/*diagnosis;
*Diet;
Dietary Proteins;
Energy Intake;
Female;
Humans;
Male;
Metabolic Syndrome X/complications;
Middle Aged;
Odds Ratio;
Retrospective Studies;
Risk Factors;
Smoking;
Waist Circumference
- From:The Korean Journal of Gastroenterology
2012;60(2):102-108
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: The role of dietary risk factors in colorectal carcinogenesis remains unclear. We investigated the association between dietary intakes and colorectal adenomas who visited a health promotion center for a routine health check-up colonoscopy. METHODS: We conducted a retrospective case-control study using data from individuals who had colonoscopy at Seoul National University Hospital Healthcare System Gangnam Center from October 2003 to December 2007. The subjects were 242 patients (162 males and 80 females) with histopathologically confirmed colorectal adenoma, and 464 (272 males and 192 females) controls. Dietary data were obtained via 24 hour dietary recall, assisted by a registered dietitian. The student's t-test and the chi-square test were performed for the statistical comparison of means and proportions among groups. Multivariate analyses using logistic regression were performed to assess the relation between dietary intake and colorectal adenoma. RESULTS: The total average energy intake of the patients (male: 2,407.5+/-429.2 kcal, female: 1,901.3+/-316.9 kcal) was higher than the controls (male: 2,249.6+/-430.4 kcal, female: 1,752.4+/-275.0 kcal; p=0.001). High energy intake (male: OR=4.13, 95% CI=1.70-10.05, p=0.002; female: OR=4.00, 95% CI=1.51-10.61, p=0.005) and animal protein intake (male: OR=3.97, 95% CI=1.66-9.49, p=0.002; female: OR=5.76, 95% CI=1.99-16.169, p=0.001) were found to be associated with the risk of colorectal adenoma after adjusting for confounders such as age, BMI, waist circumference, metabolic syndrome and smoking. CONCLUSIONS: In summary, high energy intake and animal protein were associated with colorectal adenoma.
