Incidence of Metabolic Syndrome and Relative Importance of Five Components as a Predictor of Metabolic Syndrome: 5-Year Follow-up Study in Korea.
10.3346/jkms.2013.28.12.1768
- Author:
Jun Hyun HWANG
1
;
Sin KAM
;
Ji Yeon SHIN
;
Jong Yeon KIM
;
Kyung Eun LEE
;
Gi Hong KWON
;
Byung Yeol CHUN
;
Shung Chull CHAE
;
Dong Heon YANG
;
Hun Sik PARK
;
Tae Yoon HWANG
Author Information
1. Department of Preventive Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea.
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Cohort Studies;
Incidence;
Metabolic Syndrome;
Risk Factors
- MeSH:
Adult;
Aged;
Cholesterol, HDL/blood;
Cohort Studies;
Diabetes Mellitus, Type 2/complications;
Female;
Follow-Up Studies;
Humans;
Hypertension/complications;
Hypertriglyceridemia/complications;
Incidence;
Male;
Metabolic Syndrome X/complications/*epidemiology;
Middle Aged;
Multivariate Analysis;
Obesity, Abdominal/complications;
Republic of Korea/epidemiology;
Risk Factors
- From:Journal of Korean Medical Science
2013;28(12):1768-1773
- CountryRepublic of Korea
- Language:English
-
Abstract:
The aim of this study was to describe the incidence of metabolic syndrome and to identify five components as metabolic syndrome predictors. The final study included 1,095 subjects enrolled in a rural part of Daegu Metropolitan City, Korea for a cohort study in 2003. Of these, 762 (69.6%) subjects had participated in the repeat survey. During the five-year follow-up, incidence density was significantly higher for women than for men (men, 30.0/1,000 person-years; women, 46.4/1,000 person-years). In both men and women, incidence of metabolic syndrome showed a significant increase with increasing number of metabolic syndrome components at baseline. Compared with individuals presenting none of components at baseline, relative risks were increased 1.22 (men; 95% CI, 0.43-3.51), 2.21 (women; 95% CI, 0.98-4.97) times more for individuals with one component of metabolic syndrome and 5.30 (men; 95% CI, 2.31-12.13), 5.53 (women; 95% CI, 2.78-11.01) times more for those who had two components. In multivariate analysis, the most powerful risk factor for metabolic syndrome was abdominal obesity in men and low HDL-cholesterol in women (adjusted relative risk, 3.28, 2.53, respectively). Consequently, finding a high risk group for metabolic syndrome according to gender and prevention of metabolic syndrome through lifestyle modification are essential.
