A Case of Kaposi's Sarcoma with Lymphedema in a Chronic Immunosuppressed Patient.
- Author:
Yeon Woong KIM
1
;
Byeong Su KIM
;
Jin Hwa CHOI
;
Dong Hoon SHIN
;
Jong Soo CHOI
Author Information
1. Department of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea. dhshin@med.yu.ac.kr
- Publication Type:Case Report
- Keywords:
Immunosuppressant;
Kaposi's sarcoma;
Lymphedema
- MeSH:
Biopsy;
Dermis;
Dilatation;
Endothelial Cells;
Herpesvirus 8, Human;
Humans;
Immunohistochemistry;
Immunosuppressive Agents;
Kidney Transplantation;
Leg;
Lymphatic Vessels;
Lymphedema*;
Middle Aged;
Percutaneous Coronary Intervention;
Polymerase Chain Reaction;
Sarcoma, Kaposi*;
Skin
- From:Korean Journal of Dermatology
2016;54(1):43-46
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Kaposi's sarcoma is an angioproliferative neoplasm that is derived from endothelial cells of blood and lymphatic vessels. Although the etiology is not yet clearly revealed, human herpes virus (HHV)-8 is believed to play an important role in the occurrence of Kaposi's sarcoma. A 57-year-old man presented with hyperpigmented patches on the right lower leg for 2 months. The patient received a kidney transplantation 19 years ago and has taken immunosuppressants since then. He had undergone a percutaneous coronary intervention twice, and his right lower leg was swollen for a year. We performed a skin biopsy on the right lower leg. Histopathological examination showed neovascularization and vascular dilatation in the dermis with perivascular proliferation of spindle cells. Immunohistochemistry revealed positive findings for CD31 and CD34. An HHV-8 test using polymerase chain reaction (PCR) showed positive findings. We report an interesting case of Kaposi's sarcoma presenting as hyperpigmented patches with percutaneous coronary intervention-induced lymphedema in an immunosuppressed patient.
