Treatment with High Dose Dexamethasone of Severe Thrombocytopenia in Primary Sjogren's Syndrome.
10.4078/jrd.2012.19.6.341
- Author:
Jae Wan JUN
1
;
Joong Ki BAE
;
Hyun Sung LEE
;
Jae Hee KIM
;
Hyung Wook JU
;
Seung Won CHOI
Author Information
1. Department of Internal Medicine, Ulsan University Hospital, College of Medicine, University of Ulsan, Ulsan, Korea. choisw@uuh.ulsan.kr
- Publication Type:Case Report
- Keywords:
Sjogren's syndrome;
Thrombocytopenia;
Purpura
- MeSH:
Anemia;
Autoimmune Diseases;
Dexamethasone;
Humans;
Leukopenia;
Lymphocytes;
Lymphoproliferative Disorders;
Purpura;
Sjogren's Syndrome;
Thrombocytopenia
- From:Journal of Rheumatic Diseases
2012;19(6):341-343
- CountryRepublic of Korea
- Language:English
-
Abstract:
Sjogren's syndrome is a systemic autoimmune disease characterized by sicca symptoms and B lymphocyte hyperactivity. Hematological abnormalities are common in Sjogren's syndrome, including anemia, leukopenia, thrombocytopenia, and lymphoproliferative disorders. These hematologic involvements are mostly recognized as mild laboratory abnormalities. Life-threatening, severe thrombocytopenia is very rare. We describe a patient with primary Sjogren's syndrome, who developed very severe thrombocytopenia during the clinical course and successfully treated with high dose dexamethasone therapy.
