Change of Surname?: An application of Y-STR Haplotyping.
- Author:
Ki Min SEONG
1
;
Seong Yeon YOO
;
Jung Ho HWANG
;
Nam Soo CHO
;
Seong Ho KIM
;
Young Shik CHOI
Author Information
1. Department of Forensic Medicine, Central District Office, NISI, Daejeon 305-348, Korea. cns6999@nisi.go.kr
- Publication Type:Original Article
- Keywords:
Y-STR;
surname;
haplotypes;
mutation
- MeSH:
Alleles;
Haplotypes;
Humans;
Male
- From:Korean Journal of Legal Medicine
2008;32(1):68-71
- CountryRepublic of Korea
- Language:English
-
Abstract:
Y-STR haplotyping is a powerful forensic and anthropological tool for identifying male lineages. We used high-resolution Y-STR haplotyping to evaluate the possibility of an ancestral relationship between two individuals with the different surname. Of the 17 Y-STRs genotyped, 16 had identical alleles in two individuals, except for an unambiguously sporadic mutation (one-step mutation) at DYS385 locus. The common allele 11.1 (U3Ains) at DYS439 locus was also observed in these two individuals. Sequencing analysis of these alleles of two samples demonstrated an A insertion at base 3 upstream from the repeat region's first GATA motif. These findings suggested that two individuals were paternally related, even if male individuals live with different surname.
