Pseudoxanthoma Elasticum Presenting as Localized Skin Lesion without Systemic Involvement.
- Author:
Min Soo JANG
1
;
Dong Young KANG
;
Jin Seuk KANG
;
Jae Woo BAEK
;
Sang Tae KIM
;
Kee Suck SUH
Author Information
1. Department of Dermatology, Kosin University College of Medicine, Busan, Korea. ksderm98@unitel.co.kr
- Publication Type:Case Report
- Keywords:
ABCC6 gene;
Classification;
Pseudoxanthoma elasticum
- MeSH:
Blood Vessels;
Elastic Tissue;
Neck;
Pseudoxanthoma Elasticum;
Retina;
Skin
- From:Korean Journal of Dermatology
2011;49(1):53-57
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pseudoxanthoma elasticum (PXE) is a heritable disorder of elastic tissue and it has many systemic manifestations. PXE is a systemic disorder that most markedly affects the elastic tissues in the skin, retina and blood vessels. Defects in the ABCC6 gene lead to calcification of elastic tissue. We herein report on two cases of pseudoxanthoma elasticum that presented with focal involvement on the skin of the neck without marked wrinkling.
