Severe Pulmonary Hypertension in Primary Sjogren's Syndrome.
10.4070/kcj.2013.43.7.504
- Author:
Ji An HWANG
1
;
Tae Hyun YANG
;
Ji Young LEE
;
Dong Wan KOO
;
In Suk CHOI
;
Sun Young CHO
;
Min Sung KIM
Author Information
1. Division of Cardiology, Department of Internal Medicine, Inje University College of Medicine, Cardiovascular Research Institute, Busan Paik Hospital, Busan, Korea. yangthmd@naver.com
- Publication Type:Case Report
- Keywords:
Hypertension, pulmonary;
Sjogren's syndrome
- MeSH:
Antibodies;
Azathioprine;
Cardiac Catheterization;
Cardiac Catheters;
Dyspnea;
Echocardiography;
Female;
Heart;
Humans;
Hydrogen-Ion Concentration;
Hypertension, Pulmonary;
Receptors, Endothelin;
Salivary Glands;
Sjogren's Syndrome;
Submandibular Gland;
Xerophthalmia;
Xerostomia
- From:Korean Circulation Journal
2013;43(7):504-507
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 65 year-old female with a history of xerostomia and xerophthalmia was presented with dyspnea on exertion (New York Heart Association class III). Echocardiography and cardiac catheterization demonstrated severe pulmonary hypertension (PH). Laboratory examinations showed positive anti-nuclear and anti-Ro/SS-A antibodies. Schirmer's test was positive and salivary gland scintigraphy revealed severely decreased tracer uptakes in both parotid and submandibular glands. By excluding other possible causes of PH during further examinations, she was diagnosed with severe PH associated with primary Sjogren's syndrome. Her dyspnea symptom was much improved with endothelin receptor antagonist and azathioprine.
