Is Retinal Nerve Fiber Layer Thickness Change Related to Headache Lateralization in Migraine?.
10.3341/kjo.2016.30.2.134
- Author:
Alime GUNES
1
;
Seden DEMIRCI
;
Levent TOK
;
Ozlem TOK
;
Serpil DEMIRCI
;
Süleyman KUTLUHAN
Author Information
1. Department of Ophthalmology, Süleyman Demirel University Faculty of Medicine, Isparta, Turkey. dralimesefer@hotmail.com
- Publication Type:Original Article
- Keywords:
Migraine;
Retinal nerve fiber layer thickness;
Unilateral headache
- MeSH:
Cross-Sectional Studies;
Headache*;
Humans;
Migraine Disorders*;
Nerve Fibers*;
Retinaldehyde*;
Tomography, Optical Coherence
- From:Korean Journal of Ophthalmology
2016;30(2):134-139
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To evaluate retinal nerve fiber layer (RNFL) thickness in migraine patients with unilateral headache. METHODS: A total of 58 patients diagnosed with migraine headache consistently occurring on the same side and 58 age- and sex-matched healthy subjects were evaluated in this cross-sectional study. RNFL thickness was measured using spectral-domain optical coherence tomography, and the side with the headache was com-pared with the contralateral side as well as with the results of healthy subjects. RESULTS: The mean patient age was 33.05 ± 8.83 years, and that of the healthy subjects was 31.44 ± 8.64 years (p = 0.32). The mean duration of disease was 10.29 ± 9.03 years. The average and nasal RNFL thicknesses were significantly thinner on the side of headache and on the contralateral side compared to control eyes (p < 0.05, for all). Thinning was higher on the side of the headache compared to the contralateral side; however, this difference was not statistically significant. CONCLUSIONS: The RNFL thicknesses were thinner on the side of the headache compared to the contralateral side in the migraine patients with unilateral headache, but this difference was not statistically significant.
