A Case of Acute Pancreatitis: Portal Vein Superimposed Thrombosis in a Nephritic Syndrome Patient.
10.3904/kjm.2015.88.2.212
- Author:
Nak Min KIM
1
;
Ji Hyung YOO
;
Woo Kyung SUNG
;
Su A YUN
;
Jin Uk JEONG
;
Jong Ho SHIN
;
Ki Tae BANG
Author Information
1. Department of Internal Medicine, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea. starryroom@eulji.ac.kr
- Publication Type:Case Report
- Keywords:
Nephrotic syndrome;
Pancreatitis
- MeSH:
Abdominal Pain;
Adult;
Biopsy;
Colon;
Diagnosis;
Female;
Humans;
Hyperlipidemias;
Hypoalbuminemia;
Intestine, Small;
Kidney;
Mesenteric Veins;
Nephrosis, Lipoid;
Nephrotic Syndrome;
Pancreatitis*;
Portal Vein*;
Proteinuria;
Thrombophilia;
Thrombosis*;
Veins;
Warfarin
- From:Korean Journal of Medicine
2015;88(2):212-217
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Nephrotic syndrome is characterized by hypercoagulability and thrombosis of the renal and deep veins. We describe a case of unusual thrombosis in the portal and superior mesenteric veins of a 41-year-old female, admitted for treatment of abdominal pain, who simultaneously presented with nephrotic syndrome and acute pancreatitis. Laboratory analysis revealed hypoalbuminemia, hyperlipidemia, and proteinuria. Abdominal computed tomography revealed acute pancreatitis, thrombosis at the portal and superior mesenteric veins, and ischemic changes in the colon and small intestines. Anticoagulation therapy was started immediately. Abdominal pain was subsequently reduced and the ischemic lesion disappeared. Warfarin use could not be terminated immediately. Empirical steroid therapy commenced without a kidney biopsy. Complete remission occurred after 4 weeks. Following warfarin cessation, a kidney biopsy was performed, confirming the diagnosis of minimal change disease.
