Hepatic perivascular epithelioid cell tumor (PEComa): a case report with a review of literatures.
- Author:
Hyun Jin SON
1
;
Dong Wook KANG
;
Joo Heon KIM
;
Hyun Young HAN
;
Min Koo LEE
Author Information
- Publication Type:Case Report
- Keywords: Hepatic; PEComa; HMB45; Melan A
- MeSH: Actins; Adipose Tissue; Blood Vessels; Carcinoma, Hepatocellular; Diagnostic Imaging; Epithelioid Cells*; Female; Hematopoiesis, Extramedullary; Hepatectomy; Hepatitis C, Chronic; Hepatocytes; Humans; Kidney Failure, Chronic; Liver; MART-1 Antigen; Melanoma; Middle Aged; Muscle, Smooth; Perivascular Epithelioid Cell Neoplasms
- From:Clinical and Molecular Hepatology 2017;23(1):80-86
- CountryRepublic of Korea
- Language:English
- Abstract: Hepatic perivascular epithelioid cell tumors (PEComas) are very rare. We report a primary hepatic PEComa with a review of the literature. A 56-year-old women presented with a nodular mass detected during the management of chronic renal failure and chronic hepatitis C. Diagnostic imaging studies suggested a nodular hepatocellular carcinoma in segment 5 of the liver. The patient underwent partial hepatectomy. A brown-colored expansile mass measuring 3.2×3.0 cm was relatively demarcated from the surrounding liver parenchyma. The tumor was mainly composed of epithelioid cells that were arranged in a trabecular growth pattern. Adipose tissue and thick-walled blood vessels were minimally identified. A small amount of extramedullary hematopoiesis was observed in the sinusoidal spaces between tumor cells. Tumor cells were diffusely immunoreactive for human melanoma black 45 (HMB45) and Melan A, focally immunoreactive for smooth muscle actin, but not for hepatocyte specific antigen (HSA).
