Early Detection of Hemodialysis Ateriovenous Fistula Dysfunction by Trend Analysis of Intra-access Pressure.
	    		
		   		
	    	
    	
    	
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Hyung Joon AHN
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Jong Hoon LEE
			        		
			        		;
		        		
		        		
		        		
			        		Sung Il PARK
			        		
			        		;
		        		
		        		
		        		
			        		Soo Young YOON
			        		
			        		;
		        		
		        		
		        		
			        		Sang Choel LEE
			        		
			        		;
		        		
		        		
		        		
			        		Sung Ja YANG
			        		
			        		;
		        		
		        		
		        		
			        		Yu Seun KIM
			        		
			        		;
		        		
		        		
		        		
			        		Kiil PARK
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Department of Surgery, Kwandong University College of Medicine, Goyang, Korea. hartsol@kwandong.ac.kr
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Original Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Arteriovenous fistula;
			        		
			        		
			        		
				        		Vascular stricture;
			        		
			        		
			        		
				        		Pressure;
			        		
			        		
			        		
				        		Angiography
			        		
			        		
	        			
        			
        		
 
        	
            
            	- MeSH:
            	
	        			
	        				
	        				
				        		
					        		Angiography;
				        		
			        		
				        		
					        		Arteriovenous Fistula;
				        		
			        		
				        		
					        		Constriction, Pathologic;
				        		
			        		
				        		
					        		Fistula;
				        		
			        		
				        		
					        		Humans;
				        		
			        		
				        		
					        		Renal Dialysis
				        		
			        		
	        			
	        			
            	
            	
 
            
            
            	- From:Korean Journal of Nephrology
	            		
	            		 2008;27(6):696-706
	            	
            	
 
            
            
            	- CountryRepublic of Korea
 
            
            
            	- Language:Korean
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	PURPOSE: To detect early arteriovenous fistula (AVF) dysfunction, we have developed a new method of intra-access total pressure (pT), and static pressure (pS) measurements. The purpose of this study is to assess the relationship between intra-access pressure and vascular stricture in order to establish the clinical validity of the method. METHODS: Total 46 of native AVFs were enrolled. They were measured intra-access pS and pT monthly. In initial angiography, 6 of 10 inflow stricture (As), 6 of 7 outflow stricture (Vs) and 2 having both lesions were taken PTA (percutaneous angioplasty) and compared pressure and ratio changes. If delta p (pT-pS) decreased more than 10% over 3 months or pT/MAP (mean arterial pressure) ratio dropped more than 10% over 3 months with below 0.8, then the patients were referred to angiography. Thirtyone patients were performed final angiography, and we compared the results with those of initial angiography. RESULTS: Although pT/MAP ratio and delta p were increased after PTA, there was no statistical significance in 6 As (+) patients (p>0.05). Six Vs (+) and 2 AS (+) and Vs (+) patients' delta p were increased significantly (p<0.05). Two As (+) and 5 Vs (+) were detected with delta p or pT/MAP ratio change. However, 2 Vs (+) were unable to be detected with delta p, but detected only by final angiography. Among 15 As (-) and Vs (-) patients in both initial and final angiography, pT and MAP were not reproducible (pI<0.4), but pS and delta p showed intermediate reproducibility (pI>0.45). CONCLUSION: Intra-access stricture could be detected with pT/MAP ratio and delta p change. However, more careful MAP and pT measurement should be recommended for accurate diagnosis.