A case of Tsutsugamushi disease presenting with nephrotic syndrome.
10.3904/kjim.2013.28.6.728
- Author:
Ju Hyun LEE
1
;
Mi Jung LEE
;
Dong Ho SHIN
;
Shin Wook KANG
;
Kyu Hun CHOI
;
Tae Hyun YOO
Author Information
1. Division of Nephrology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. YOOSY0316@yuhs.ac
- Publication Type:Case Reports
- Keywords:
Nephrotic syndrome;
Scrub typhus;
Glomerulonephritis;
Membranous
- MeSH:
Aged;
Anti-Bacterial Agents/therapeutic use;
Antibodies, Bacterial/blood;
Biopsy;
Doxycycline/therapeutic use;
Female;
Glomerulonephritis, Membranous/diagnosis/*etiology;
Humans;
Nephrotic Syndrome/diagnosis/*etiology;
Orientia tsutsugamushi/immunology;
Scrub Typhus/*complications/diagnosis/drug therapy/microbiology;
Treatment Outcome
- From:The Korean Journal of Internal Medicine
2013;28(6):728-731
- CountryRepublic of Korea
- Language:English
-
Abstract:
Nephrotic syndrome associated with Tsutsugamushi disease has not been previously reported. We are describing a case of Tsutsugamuchi disease presenting with nephrotic syndrome. A 72-year-old woman presented with fever and generalized edema. Laboratory studies revealed a leukocytosis, hypoalbuminemia, and hypercholesterolemia. Her urine protein excretion was 5.4 g/day. The anti-Tsutsugamushi antibody test was strongly positive (1:2,560). A renal biopsy was performed, and pathologic findings revealed membranous glomerulonephritis. The patient's clinical symptoms improved markedly after treatment with doxycycline.
