Virilizing Adrenocortical Oncocytoma in a Child: A Case Report.
10.3346/jkms.2010.25.7.1077
- Author:
Yeon Jung LIM
1
;
Se Min LEE
;
Jae Hun SHIN
;
Hyun Chul KOH
;
Young Ho LEE
Author Information
1. Department of Pediatrics, Hanyang University College of Medicine, Seoul, Korea. cord@hanyang.ac.kr
- Publication Type:Case Report ; Research Support, Non-U.S. Gov't
- Keywords:
Adrenal Cortex Neoplasms;
Adenoma, Oxyphilic;
Virilism;
Child
- MeSH:
Adenoma, Oxyphilic/*complications/metabolism/pathology/surgery;
Adolescent;
Adrenal Cortex Neoplasms/*complications/metabolism/pathology/surgery;
Adrenalectomy;
Adult;
Female;
Humans;
Male;
Middle Aged;
Virilism/*etiology/pathology/surgery
- From:Journal of Korean Medical Science
2010;25(7):1077-1079
- CountryRepublic of Korea
- Language:English
-
Abstract:
Functioning adrenocortical oncocytomas are extremely rare and most reported patients are 40-60 yr of age. To our knowledge, only 2 cases of functioning adrenocortical oncocytomas have been reported in childhood. We report a case of functioning adrenocortical oncocytoma in a 14-yr-old female child presenting with virilization. She presented with deepening of the voice and excessive hair growth, and elevation of plasma testosterone and dehydroepiandrosterone sulfate. She had an adrenalectomy. The completely resected tumor composed predominantly of oncocytes without atypical mitosis and necrosis. A discussion of this case and a review of the literature on this entity are presented.
