Autoimmune hepatitis and thyroiditis associated with antituberculous medications: A case report.
10.3345/kjp.2008.51.5.528
- Author:
Seong Keun YU
1
;
Sara KIM
;
Jin Soo MOON
;
Han Seong KIM
Author Information
1. Department of Pediatrics, Inje University Ilsan Paik Hospital, Goyang, Korea. jsmoon@ilsanpaik.ac.kr
- Publication Type:Case Report
- Keywords:
Toxic hepatitis;
Autoimmune thyroiditis;
Isoniazid;
Rifampin
- MeSH:
Autoantibodies;
Child;
Drug-Induced Liver Injury;
Hepatitis;
Hepatitis, Autoimmune;
Humans;
Interferons;
Isoniazid;
Korea;
Methyldopa;
Minocycline;
Nitrofurantoin;
Rifampin;
Thyroid Gland;
Thyroiditis;
Thyroiditis, Autoimmune
- From:Korean Journal of Pediatrics
2008;51(5):528-532
- CountryRepublic of Korea
- Language:English
-
Abstract:
Drug-induced toxic hepatitis is a relatively common hepatic disease in children, and it is usually self-limiting upon cessation of the offending drugs. Antituberculous drugs are well known for inducing hepatitis. Some cases of drug-induced hepatitis with autoimmune features have been reported; in these cases, the offending drugs were usually methyldopa, nitrofurantoin, minocycline, and interferon. The authors report the first case in Korea of drug-induced autoimmune hepatitis associated with thyroiditis and multiple autoantibodies that was induced by the antituberculous drugs isoniazid and rifampin.
