The Seroprevalence Rate, Vaccination Rate and Seroconversion Rate of Hepatitis A in Central Region of Korea.
10.4166/kjg.2011.57.3.166
- Author:
Seung Wook YUN
1
;
Won Kyung LEE
;
Sun Young CHO
;
Sung Hoon MOON
;
Hyun Deok SHIN
;
Se Young YUN
;
Suk Bae KIM
;
Jeong Eun SHIN
;
Hong Ja KIM
;
Il Han SONG
;
Kun Song LEE
;
Jae Hyun LEE
Author Information
1. Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea. sm1213@paran.com
- Publication Type:Original Article ; English Abstract ; Research Support, Non-U.S. Gov't
- Keywords:
Seroprevalence rate;
Vaccination rate;
Seroconversion rate;
Hepatitis A
- MeSH:
Adolescent;
Adult;
Aged;
Aged, 80 and over;
Child;
Child, Preschool;
Female;
Hepatitis A/*epidemiology/prevention & control;
Hepatitis A Antibodies/*blood;
*Hepatitis A Vaccines;
Hepatitis A Virus, Human/immunology;
Humans;
Immunoglobulin G/blood;
Male;
Middle Aged;
Republic of Korea;
Seroepidemiologic Studies
- From:The Korean Journal of Gastroenterology
2011;57(3):166-172
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: Acute hepatitis A (HAV) is markedly increasing recently on. Some patients with acute hepatitis A show severe clinical course. The seroprevalence rate of IgG anti-HAV has been changing with the regions and the times. Vaccination and seroconversion rate of HAV are not well known. In this study, we aimed to study the difference of seroprevalence rate of IgG anti-HAV according to various clinical factors and to know the vaccination rate and seroconversion rate below 10 years old in the central region of South Korea including Cheonan city. METHODS: Seven hundred seventy two subjects were included in the study from January to September 2009. We analyzed seroprevalence rate of IgG anti-HAV according to sex, age, region, and other viral markers. We interviewed the history of vaccination(1st, 2nd) and analyzed seroconversion rate according to vaccination time below 10 years old. RESULTS: The total seroprevalence rate of IgG anti-HAV was 65.3%. The seroprevalence rate of IgG anti-HAV rate in 2nd, 3rd, and 4th decade was very low (1.9%, 18.8%, 44.8%). The vaccination rate of children was about 50%. The seroconversion rate after 1st, and 2nd vaccination were 85%, 96%. CONCLUSIONS: Catch-up vaccination for teenagers and young adults is needed. Immunizing children with HAV vaccine as a routine schedule should be considered.
