Effect of Muscle Relaxants on Short-term Results of Exotropia Surgery: A Focus on Resection Procedures.
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3341/kjo.2008.22.4.246
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Young Suk CHANG
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Seung Hee BAEK
			        		
			        		;
		        		
		        		
		        		
			        		Jeong Min PARK
			        		
			        		;
		        		
		        		
		        		
			        		Hee Uk KWON
			        		
			        		;
		        		
		        		
		        		
			        		Yong Ran KIM
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Department of Ophthalmology, Konyang University Hospital, Konyang University College of Medicine, Daejeon, Korea.
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Original Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Atracurium;
			        		
			        		
			        		
				        		Extraocular muscles;
			        		
			        		
			        		
				        		General anesthesia;
			        		
			        		
			        		
				        		Intermittent exotropia;
			        		
			        		
			        		
				        		Muscle relaxant
			        		
			        		
	        			
        			
        		
 
        	
            
            	- MeSH:
            	
	        			
	        				
	        				
				        		
					        		Anesthesia, Inhalation;
				        		
			        		
				        		
					        		Atracurium/*administration & dosage;
				        		
			        		
				        		
					        		Child;
				        		
			        		
				        		
					        		Child, Preschool;
				        		
			        		
				        		
					        		Exotropia/*physiopathology/*surgery;
				        		
			        		
				        		
					        		Female;
				        		
			        		
				        		
					        		Humans;
				        		
			        		
				        		
					        		Injections, Intravenous;
				        		
			        		
				        		
					        		Male;
				        		
			        		
				        		
					        		Muscle Relaxation;
				        		
			        		
				        		
					        		Neuromuscular Nondepolarizing Agents/*administration & dosage;
				        		
			        		
				        		
					        		Oculomotor Muscles/*physiopathology;
				        		
			        		
				        		
					        		Ophthalmologic Surgical Procedures;
				        		
			        		
				        		
					        		Treatment Outcome
				        		
			        		
	        			
	        			
            	
            	
 
            
            
            	- From:Korean Journal of Ophthalmology
	            		
	            		 2008;22(4):246-250
	            	
            	
 
            
            
            	- CountryRepublic of Korea
 
            
            
            	- Language:English
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	PURPOSE: We investigated the effect of muscle relaxants (atracurium) on the outcomes of intermittent exotropia surgery under general anesthesia, with a focus on resection procedures. METHODS: Thirty four patients who underwent recession and resection (R&R) were divided into two groups: atracurium usage (group A, n=18) and no atracurium usage (group B, n=16). Patients were divided into two subgroups according to the amount of resection of the medial rectus (MR): less than 5 mm (group 1, n=13) or 5 mm and greater (group 2, n=21). Deviation angles were compared between groups and subgroups. Surgical outcome was defined as successful if distant deviation angles were equal to or less than 10 prism diopters. RESULTS: The overall postoperative deviation angles did not show statistically significant differences between groups A and B. However, in patients with larger MR resections (> or = 5 mm), the 1 week postoperative distant deviation was significantly larger in group A (1.8+/-2.6 PD) than in group B (-1.6+/-4.6 PD, p=0.048 by t-test). The overall undercorrection rate at 3 months postoperatively for group A was 16.7%, which was higher than that of group B (6.3%), and the difference was even larger in subgroups with larger MR resections (> or =5 mm): 18.2% in group A and 0% in group B. CONCLUSIONS: Patients who underwent R&R procedures under general anesthesia with a muscle relaxant tended to be less corrected than those without muscle relaxant, especially in the early postoperative period and with a larger MR resection equal to or greater than 5 mm. However, there was no significant difference in the later postoperative period.