A Case of Steroid Glaucoma in a Child Treated with Systemic Steroid as Graft-Versus-Host Disease.
10.3341/jkos.2016.57.3.518
- Author:
Doo Ri EO
1
;
Jong Chul HAN
;
Chang Won KEE
Author Information
1. Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. ckee@skku.edu
- Publication Type:Case Report
- Keywords:
Oral prednisolone;
Steroid-induced glaucoma;
Systemic steroid
- MeSH:
Anemia, Aplastic;
Child*;
Glaucoma*;
Graft vs Host Disease*;
Headache;
Hematopoietic Stem Cell Transplantation;
Humans;
Intraocular Pressure;
Lung;
Male;
Mitomycin;
Nausea;
Papilledema;
Prednisolone;
Steroids;
Trabeculectomy;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
2016;57(3):518-523
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report a case of steroid-induced glaucoma in a child who was treated with systemic steroids for a long period due to graft-versus-host disease. CASE SUMMARY: A 10-year-old male was referred to our ophthalmologic clinic for examination of papilledema due to persistent headache and nausea. He was diagnosed as aplastic anemia 8 years prior and took approximately 4,000 mg of oral prednisolone for 8 years from April 2007 to April 2015 for treatment of lung graft-versus-host disease after hematopoietic stem cell transplantation. His best corrected visual acuity was 0.8 (decimal) in the right eye, 0.5 in the left eye and intraocular pressure (IOP) measured using a Goldmann applanation tonometer was 42 mm Hg in the right eye and 43 mm Hg in the left eye. His cup-to-disc ratio was 0.8 in the right eye and 0.7 in the left eye. Additionally, superior and inferior neuroretinal rim thinning was present in both eyes. Despite using IOP-lowering agents, IOP was not controlled. However, after trabeculectomy with mitomycin C in both eyes, IOP became normalized. CONCLUSIONS: In cases of pediatric patients treated with systemic steroids for a long period of time, regular observation is necessary to prevent IOP elevation and steroid-induced glaucoma.
