Intravitreal Tissue Plasminogen Activator and Gas Injection in Submacular Hemorrhage.
- Author:
Il Kyung KIM
1
;
Duk Kee HAHN
Author Information
1. Department of Ophthalmology, College of Medicine, Yeungnam University, Taegu, Korea.
- Publication Type:Original Article
- Keywords:
gas;
submacular hemorrhage;
tissue plasminogen activator
- MeSH:
Aged, 80 and over;
Female;
Hemorrhage*;
Humans;
Intravitreal Injections;
Macular Degeneration;
Plasminogen;
Tissue Plasminogen Activator*
- From:Journal of the Korean Ophthalmological Society
1997;38(10):1870-1874
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Tissue plasminogen activator(tPA) has been used as useful adjunct in the submacular hemorrhage due to age-related macular degeneration, which was injected and able to dissolve clotted blood. It was also known that intravitreal injection of tPA was effective as much as subretinal injection for lysis of blood. Recently, the rationale was introduced that residual dissolved subretinal blood with tPA was displaced from fovea away by intravitreal injection of an expanding gas. We have experienced the improvement of vision in an 83-year old woman with submacular hemorrhage, treated with intravitreal tPA and gas injection.