Shock Duration after Resuscitation Is Associated with Occurrence of Post-Cardiac Arrest Acute Kidney Injury.
10.3346/jkms.2015.30.6.802
- Author:
Yong Won KIM
1
;
Kyoung Chul CHA
;
Yong Sung CHA
;
Oh Hyun KIM
;
Woo Jin JUNG
;
Tae Hoon KIM
;
Byoung Keun HAN
;
Hyun KIM
;
Kang Hyun LEE
;
Eunhee CHOI
;
Sung Oh HWANG
Author Information
1. Department of Emergency Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea. shwang@yonsei.ac.kr
- Publication Type:Original Article ; Observational Study
- Keywords:
Cardiac Arrest;
Resuscitation;
Acute Kidney Injury;
Renal Failure;
Heart Arrest;
Post-cardiac Arrest Syndrome;
Renal Replacement Therapy
- MeSH:
Acute Kidney Injury/*mortality/*therapy;
Aged;
Female;
Heart Arrest/*mortality/*therapy;
Humans;
Incidence;
Male;
Middle Aged;
Renal Replacement Therapy/mortality;
Republic of Korea/epidemiology;
Resuscitation/*mortality;
Retrospective Studies;
Risk Factors;
Severity of Illness Index;
Shock/*mortality;
Survival Rate;
Treatment Outcome
- From:Journal of Korean Medical Science
2015;30(6):802-807
- CountryRepublic of Korea
- Language:English
-
Abstract:
This retrospective observational study investigated the clinical course and predisposing factors of acute kidney injury (AKI) developed after cardiac arrest and resuscitation. Eighty-two patients aged over 18 yr who survived more than 24 hr after cardiac arrest were divided into AKI and non-AKI groups according to the diagnostic criteria of the Kidney Disease/Improving Global Outcomes (KDIGO) Clinical Practice Guidelines for AKI. Among 82 patients resuscitated from cardiac arrest, AKI was developed in 66 (80.5%) patients (AKI group) leaving 16 (19.5%) patients in the non-AKI group. Nineteen (28.8%) patients of the AKI group had stage 3 AKI and 7 (10.6%) patients received renal replacement therapy during admission. The duration of shock developed within 24 hr after resuscitation was shorter in the non-AKI group than in the AKI group (OR 1.02, 95% CI 1.01-1.04, P < 0.05). On Multiple logistic regression analysis, the only predisposing factor of post-cardiac arrest AKI was the duration of shock. In conclusion, occurrence and severity of post-cardiac arrest AKI is associated with the duration of shock after resuscitation. Renal replacement therapy is required for patients with severe degree (stage 3) post-cardiac arrest AKI.
