Clinical and Laboratory Characteristics of Pandemic Influenza A/H1N1 2009 Infection among Patients with Malignancy in Korea.
- Author:
Hyeon Jeong GOONG
1
;
Yu Ri SEO
;
La Young YOON
;
Soon Ha KWON
;
Eun Jung LEE
;
Min Hyok JEON
;
Tae Hyong KIM
;
Dae Sik HONG
;
Eun Ju CHOO
Author Information
- Publication Type:Original Article
- Keywords: Pandemic influenza A/H1N1 2009; Malignancy
- MeSH: Humans; Immunosuppressive Agents; Influenza, Human; Korea; Medical Records; Pandemics; Respiratory Tract Infections
- From:Infection and Chemotherapy 2012;44(1):1-4
- CountryRepublic of Korea
- Language:Korean
- Abstract: BACKGROUND: Patients with malignancy are considered to be at high risk of severe pandemic influenza A/H1N1 2009. This study was conducted to identify the severity of pandemic influenza A/H1N1 2009 among patients with malignancy. MATERIALS AND METHODS: Between August 2009 and December 2009, we reviewed clinical data and medical records of 31 patients with malignancy and 63 hospitalized patients without malignancy. RESULTS: Eighty-three patients with laboratory-confirmed pandemic influenza A/H1N1 2009 were admitted. The rate of ICU admission was higher among patients with malignancy (without malignancy 13% vs with malignancy 35%, P=0.024). The mortality rate was higher among patients with malignancy (without malignancy 6% vs with malignancy 25%, P=0.033). Patients using immunosuppressants showed a higher rate of lower respiratory tract infection (83% vs 24%, P=0.013). CONCLUSIONS: Pandemic influenza A/H1N1 2009 in patients with malignancy was more severe than in patients without malignancy.
