Heart Transplantation in the Elderly Patients: Midterm Results.
10.5090/kjtcs.2013.46.2.111
- Author:
Sang Yoon YEOM
1
;
Ho Young HWANG
;
Se Jin OH
;
Hyun Jai CHO
;
Hae Young LEE
;
Ki Bong KIM
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Korea. kimkb@snu.ac.kr
- Publication Type:Original Article
- Keywords:
Heart transplantation;
Outcome assessment;
Elderly
- MeSH:
Aged;
Follow-Up Studies;
Freedom;
Heart;
Heart Transplantation;
Humans;
Life Expectancy;
Rejection (Psychology);
Renal Insufficiency;
Risk Factors;
Tissue Donors
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2013;46(2):111-116
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Heart transplantation in elderly patients has raised concerns because of co-morbidities and limited life expectancy in the era of donor shortage. We examined the outcomes after heart transplantation in elderly patients. MATERIALS AND METHODS: From March 1994 to December 2011, 81 patients (male:female=64:17, 49.1+/-14.0 years) underwent heart transplantation. The outcomes after heart transplantation in the younger patients (<60 years; group Y, n=60) were compared with those in the elderly patients (> or =60 years; group O, n=21). The follow-up duration was 51.8+/-62.7 months. RESULTS: Early mortality (< or =30 days) occurred in 5.0% (3/60) and 4.8% (1/21) of groups Y and O, respectively (p>0.999). There were no differences in overall survival between the two groups (p=0.201). Freedom from rejection was higher in group O than in group Y (p=0.026). Multivariable analysis revealed that age > or =60 years was not a significant risk factor for long-term survival; postoperative renal failure was the only significant risk factor for long-term survival (p=0.011). CONCLUSION: Early and mid-term results of heart transplantation in elderly patients were similar to those in younger patients.
