An unexpected increase of entropy in a sleepwalking disorder patient during propofol and remifentanil anesthesia: a case report.
	    		
		   		
		   			
		   		
	    	
    	 
    	10.4097/kjae.2014.67.4.270
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yoon Ji CHOI
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Koo KWON
			        		
			        		;
		        		
		        		
		        		
			        		Go Eun BAE
			        		
			        		;
		        		
		        		
		        		
			        		Seung Zhoo YOON
			        		
			        		;
		        		
		        		
		        		
			        		Hye Won LEE
			        		
			        		;
		        		
		        		
		        		
			        		Hae Ja LIM
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Department of Anesthesiology and Pain Medicine, Inje University Seoul Paik Hospital, Seoul, Korea.
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Case Report
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Anesthetics;
			        		
			        		
			        		
				        		Entropy;
			        		
			        		
			        		
				        		Somnambulism
			        		
			        		
	        			
        			
        		
 
        	
            
            	- MeSH:
            	
	        			
	        				
	        				
				        		
					        		Anesthesia*;
				        		
			        		
				        		
					        		Anesthesia, General;
				        		
			        		
				        		
					        		Anesthetics;
				        		
			        		
				        		
					        		Brain;
				        		
			        		
				        		
					        		Clonazepam;
				        		
			        		
				        		
					        		Entropy*;
				        		
			        		
				        		
					        		Female;
				        		
			        		
				        		
					        		Humans;
				        		
			        		
				        		
					        		Metabolism;
				        		
			        		
				        		
					        		Middle Aged;
				        		
			        		
				        		
					        		Paroxetine;
				        		
			        		
				        		
					        		Propofol*;
				        		
			        		
				        		
					        		Somnambulism*;
				        		
			        		
				        		
					        		Suburethral Slings;
				        		
			        		
				        		
					        		Valproic Acid
				        		
			        		
	        			
	        			
            	
            	
 
            
            
            	- From:Korean Journal of Anesthesiology
	            		
	            		 2014;67(4):270-274
	            	
            	
 
            
            
            	- CountryRepublic of Korea
 
            
            
            	- Language:English
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	We report a case of increased values of entropy parameters Response Entropy (RE) and State Entropy (SE) during intravenous general anesthesia in a sleepwalking patient. An ASA class II, 64-year-old woman with stress incontinence underwent mid-urethral sling surgery. Prior to surgery, the patient had been administered paroxetine, valproic acid and clonazepam for the treatment of sleepwalking disorder. After 10 min of target-controlled infusion of propofol and remifentanil, entropy values increased up to 94 (RE) and 88 (SE) for 10 min. The target effect-site concentrations of anesthetics increased from 4 to 7 microg/ml propofol and 4 ng/ml remifentanil, at which point values fell back to adequate anesthesia levels. Episodes of recall or of explicit memories did not occur during the anesthesia. In conclusion, sleepwalking patients with long-term use medications may need increment of anesthetic dose caused by the anesthetic drug metabolism activation or impairment or immaturity of inhibitory circuits in brain.