Efficacy of Intravitreal Triamcinolone Acetonide for Eyes with Postvitrectomy Diabetic Vitreous Hemorrhage.
10.3341/kjo.2007.21.4.208
- Author:
Sun Young LEE
1
;
Hee Gyung LEE
;
Hyewon CHUNG
;
Young Hee YOON
;
June Gone KIM
Author Information
1. Department of Ophthalmology, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, Korea. dropkim@dreamwiz.com
- Publication Type:Original Article ; Comparative Study
- Keywords:
Diabetic vitreous hemorrhage;
Intravitreal triamcinolone injection;
Postvitrectomy;
Recurrent vitreous hemorrhage
- MeSH:
Adult;
Aged;
Diabetic Retinopathy/*complications/diagnosis;
Female;
Follow-Up Studies;
Glucocorticoids/*administration & dosage;
Humans;
Injections;
Male;
Microscopy, Acoustic;
Middle Aged;
Postoperative Hemorrhage/diagnosis/*drug therapy/etiology;
Retrospective Studies;
Time Factors;
Treatment Outcome;
Triamcinolone Acetonide/*administration & dosage;
Visual Acuity;
Vitrectomy/*adverse effects;
Vitreous Body;
Vitreous Hemorrhage/diagnosis/*drug therapy/etiology
- From:Korean Journal of Ophthalmology
2007;21(4):208-212
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To evaluate the efficacy of intravitreal triamcinolone acetonide (IVT) for the management of postvitrectomy diabetic vitreous hemorrhage. METHODS: The authors conducted a retrospective study of patients with postvitrectomy diabetic vitreous hemorrhage who were administered 4 mg (0.1 cc) of triamcinolone acetonide ophthalmic suspension. Ocular history, adverse events, BCVA, intraocular pressure, external eye examination, slit-lamp biomicroscopy, fundus examination, B-scan ultrasonography, and fundus photography were assessed on day 1, weeks 1, 2, and 4 and months 2 and 3. RESULTS: There were 19 eyes of 18 consecutive patients with mean follow-up after IVT injection of 28 weeks. Of the 19 eyes, 17 eyes (89%) experienced clearing of vitreous hemorrhage within 1 to 5 weeks (mean, 1.7 weeks) with visible triamcinolone precipitates along with blood clot in the inferior aspect of fundus. Of these 17 eyes, 12 eyes (63%) maintained vitreous hemorrhage-free condition at last follow-up with a mean visual acuity of 20/63 (range, 20/320 20/25), whereas 5 (29%) developed recurrent vitreous hemorrhage after clearing of vitreous hemorrhage. Vitreous hemorrhage was not cleared in 2 eyes, which required surgical procedures. CONCLUSIONS: IVT injection may be beneficial for clearing recurrent postvitrectomy Diabetic Vitreous Hemorrhage.
