The Synergy Effect of Weight-Bearing Circuit Training and Aloe QDM Complex on Obese Middle Aged Women: a Randomized Double-Blind Controlled Trial.
	    		
		   		
		   			
		   		
	    	
    	 
    	10.15384/kjhp.2014.14.2.59
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Mi Jung CHOI
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Yong An KIM
			        		
			        		;
		        		
		        		
		        		
			        		Eunju SHIN
			        		
			        		;
		        		
		        		
		        		
			        		Seon Gil DO
			        		
			        		;
		        		
		        		
		        		
			        		Wook SONG
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Health and Exercise Science Laboratory, Institute of Sports Science, Department of Physical Education, College of Education, Seoul National University, Seoul, Korea. songw3@snu.ac.kr
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Randomized Controlled Trial ; Original Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Obesity;
			        		
			        		
			        		
				        		Exercise;
			        		
			        		
			        		
				        		Aloe
			        		
			        		
	        			
        			
        		
 
        	
            
            	- MeSH:
            	
	        			
	        				
	        				
				        		
					        		Absorptiometry, Photon;
				        		
			        		
				        		
					        		Adenosine;
				        		
			        		
				        		
					        		Adipose Tissue;
				        		
			        		
				        		
					        		Aloe*;
				        		
			        		
				        		
					        		Body Composition;
				        		
			        		
				        		
					        		Body Weight;
				        		
			        		
				        		
					        		Cytokines;
				        		
			        		
				        		
					        		Fasting;
				        		
			        		
				        		
					        		Female;
				        		
			        		
				        		
					        		Hand Strength;
				        		
			        		
				        		
					        		Humans;
				        		
			        		
				        		
					        		Hyperlipidemias;
				        		
			        		
				        		
					        		Insulin Resistance;
				        		
			        		
				        		
					        		Metabolic Diseases;
				        		
			        		
				        		
					        		Middle Aged*;
				        		
			        		
				        		
					        		Obesity;
				        		
			        		
				        		
					        		Physical Fitness;
				        		
			        		
				        		
					        		Pliability;
				        		
			        		
				        		
					        		Risk Factors;
				        		
			        		
				        		
					        		Soybeans;
				        		
			        		
				        		
					        		Weight-Bearing*
				        		
			        		
	        			
	        			
            	
            	
 
            
            
            	- From:Korean Journal of Health Promotion
	            		
	            		 2014;14(2):59-66
	            	
            	
 
            
            
            	- CountryRepublic of Korea
 
            
            
            	- Language:Korean
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	BACKGROUND: Obesity is a major health problem and leads to metabolic diseases such as type 2 diabetes, insulin resistance and hyperlipidemia. Recently, it was reported that aloe QDM complex, composed of processed aloe vera gel, aloesin and chromiun could improve insulin sensitivity by enhancing 5' adenosine monophosphate-activated protein (AMPK) activity and has an anti-inflammatory effect by reducing the level of pro-inflammatory cytokines. It is also known that aloe QDM complex can reduce body weight, body fat mass and insulin resistance in type 2 diabetes patients. The purpose of this study was to assess for possible synergistic effects of weight-bearing circuit training and aloe QDM complex supplementation on body composition, physical fitness, blood profile and diabetes risk factors. METHODS: Study subjects included 19 participants randomly assigned to the Exercise group (Ex, n=9) and to the Exercise with aloe QDM complex group (Q-Ex, n=10). Both groups participated in weight-bearing circuit training 3 times a week for 4 weeks and took a capsule composed of either aloe (aloe QDM complex) or soy bean (placebo), 1100 mg/day for 4 weeks. Body composition was measured by dual-energy x-ray absorptiometry. Grip strength, flexibility, curl-up, balance, agility, Sargent jump and VO2max were measured, as well as fasting blood samples taken. RESULTS: After 4 weeks of weight-bearing circuit training and aloe QDM complex supplementation, the significant interactions (time x intervention) between the groups regarding body fat percentage (F=7.024, P=0.017) and body fat mass (F=5.243, P=0.035) were calculated. There were significant differences in body fat percentage (P=0.029) and body fat mass (P=0.039). No significant interaction was observed in physical fitness, blood profile and diabetes risk factors. CONCLUSIONS: In this study, the combination of weight-bearing circuit training and aloe QDM complex supplementation showed a positive effect for reducing body fat mass, and could be an effective intervention for managing obesity.