Simplified Correction of Ischemic Index in Diabetic Retinopathy Evaluated by Ultra-widefield Fluorescein Angiography.
10.3341/kjo.2015.29.3.168
- Author:
Jeong Hee KIM
1
;
Hyeong Gi JUNG
;
Hye Jin CHUNG
;
Kyungmin LEE
;
Joonhong SOHN
Author Information
1. HanGil Eye Hospital, Incheon, Korea. jhsohn19@hanafos.com
- Publication Type:Original Article
- Keywords:
Diabetic retinopathy;
Ischemic index;
Wide-field fluorescein angiography
- MeSH:
Adult;
Aged;
Aged, 80 and over;
Diabetic Retinopathy/*diagnosis/pathology;
Female;
Fluorescein Angiography/*methods;
Humans;
Ischemia/pathology;
Male;
Middle Aged;
Retinal Vein/pathology;
Retrospective Studies;
Sensitivity and Specificity
- From:Korean Journal of Ophthalmology
2015;29(3):168-172
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To develop a novel, simplified method for correcting the ischemic index of nonperfused areas in diabetic retinopathy (DR). METHODS: We performed a retrospective review of 103 eyes with naive DR that underwent ultra-widefield angiography (UWFA) over a year. UWFAs were graded according to the quantity of retinal non-perfusion, and uncorrected ischemic index (UII) and corrected ischemic index (CII) were calculated using a simplified, novel method. RESULTS: The average differences between UII and CII in the non-proliferative DR group and the proliferative DR group were 0.7 +/- 0.9% in the <25% CII group, 3.0 +/- 0.9% in the 25% to 49.9% CII group, and 3.6 +/- 0.6% in the >50% CII group, respectively. A CII >25% was critical for determining DR progression (p < 0.001). CONCLUSIONS: Distortion created by UWFA needs to be corrected because the difference between UII and CII in DR increases with the ischemic index.
