Stereotactic Body Radiotherapy for Isolated Para-aortic Lymph Node Recurrence after Curative Resection in Gastric Cancer.
10.3346/jkms.2009.24.3.488
- Author:
Mi Sook KIM
1
;
Sung Yul YOO
;
Chul Koo CHO
;
Hyung Jun YOO
;
Kwang Mo YANG
;
Jin Kyu KANG
;
Dong Han LEE
;
Jong Inn LEE
;
Ho Youn BANG
;
Min Suk KIM
;
Hae Jin KANG
Author Information
1. Department of Radiation Oncology, Korea Institute of Radiological & Medical Sciences, Seoul, Korea. mskim@kcch.re.kr
- Publication Type:Original Article
- Keywords:
Stomach Neoplasms;
Recurrence;
Radiotherapy
- MeSH:
Adult;
Aged;
Disease-Free Survival;
Female;
Humans;
Lymph Nodes/surgery;
Lymphatic Metastasis;
Male;
Middle Aged;
Neoplasm Recurrence, Local/*radiotherapy/surgery;
Radiosurgery;
Radiotherapy Dosage;
Recurrence;
Stomach Neoplasms/diagnosis/pathology/*surgery;
Survival Analysis
- From:Journal of Korean Medical Science
2009;24(3):488-492
- CountryRepublic of Korea
- Language:English
-
Abstract:
The aim of this study was to investigate whether stereotactic body radiotherapy (SBRT) can salvage gastric cancer patients with para-aortic lymph node (PALN) recurrence. From January 2003 to December 2006, 7 patients were treated for isolated PALN recurrence from gastric cancer after curative resection. Follow up durations ranged from 19 to 33 months (median; 26 months), and SBRT doses from 45 Gy to 51 Gy (median 48 Gy) in 3 fractions. Disease progression-free and overall survivals and toxicities were recorded. Response to treatment was assessed by computed tomography. Final patient outcomes were as follows: 2 were alive without evidence of disease, 3 remained alive with disease, and 2 patients died of disease. Five of 7 patients showed complete response and 2 patients partial response between 3 and 11 months after SBRT. Three-year overall and disease progression-free survival rates post-SBRT were 43% and 29%, respectively. No severe complication was detected during follow-up. Selected patients with isolated PALN recurrence can be salvaged by SBRT without severe complications.
