Central Retinal Artery Obstruction in Protein S Deficiency.
10.3341/jkos.2008.49.12.2017
- Author:
Sung Bok LEE
1
;
Yong Jun YUN
;
Jung Yeul KIM
Author Information
1. Department of Ophthalmology, College of Medicine, Chungnam National Univercity, Deajeon, Korea. kimjy@cnu.ac.kr
- Publication Type:Case Report
- Keywords:
Central retinal artery obstruction;
Hypercoagulable state;
Protein S
- MeSH:
Adult;
Antibodies, Anticardiolipin;
Antithrombin III;
Blood Coagulation Factors;
Blood Coagulation Tests;
Diabetes Mellitus;
Eye;
Hematologic Tests;
Humans;
Hypertension;
Light;
Protein C;
Protein S;
Protein S Deficiency;
Pupil Disorders;
Retinal Artery;
Retinaldehyde;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
2008;49(12):2017-2020
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report a case of central retinal artery obstruction (CRAO) caused by protein S deficiency. CASE SUMMARY: A 36-year-old man presented with acutely reduced visual acuity in the right eye. The patient had no other diseases such as diabetes mellitus or hypertension. The visual acuity was 20/20 in the right eye and light perception in the left eye. Afferent pupillary defect was observed in theleft eye. Fundus examination showed diffuse retinal opacification and a cherry-red spot at the macula. Thus the patient was diagnosed with CRAO in the left eye. There were no abnormal findings on routine hematologic tests including blood coagulation test. Protein C activity, antithrombin III activation, anticardiolipin antibody were within normal limits but protein S activity was decreased. Thus, the patient was diagnosed with CRAO with protein S deficiency. CONCLUSIONS: Coagulation factors such as protein S need to be measuredin cases of CRAO in young patients without medical problems.
